Open microbial systems-biology resource
Map the molecular logic of microbial chain elongation.绘制微生物链延长的分子机制图谱
A Comparative Genomics Resource for Microbial Chain Elongation and Medium Chain Fatty Acids Biosynthesis
Connected knowledge layers
Move from organism identity to a testable production design.
Search interlinked biological and process evidence instead of disconnected lists.
01 · ORGANISM LAYER🦠
Functional organisms
Taxonomy, strain identity, physiological roles, substrates, products, cultivation context, assemblies and evidence.
Explore organisms → 02 · CHEMISTRY LAYER◈Carbon and redox flow
Follow feedstock-derived substrates, intermediates, cofactors and chain-length products across MCFA synthesis.
Explore production design → 03 · FUNCTIONAL LAYER⌘Genes, enzymes and orthologs
Connect protein evidence and orthogroups to catalytic steps, pathway completeness and energy conservation.
Explore orthology →Mechanism explorer
Start with the mechanisms that determine chain length and product formation.
Compare how carbon is extended, reducing equivalents are balanced, and genes and enzymes control the route from waste-derived substrates to MCFAs.
↻Reverse β-oxidation (chain elongation)CoA-dependent cyclic addition of two-carbon acetyl units. Acetyl-CoA is condensed with an acyl-CoA, reduced, dehydrated and reduced again; termi…⟷Fatty acid biosynthesis (FAS II)ACP-dependent elongation using malonyl-ACP as the two-carbon donor. This alternative proposed route requires ATP for malonyl-CoA formation and a…
⚡Synergistic community designCombine genomic capability with cross-feeding and culture compatibility.
Ethanol / lactateelectron input
Genes & enzymesThl · Hbd · Crt · Bcd/Etf
Electron flowNADH · ferredoxin · Rnf
C6 / C8 productscaproate · caprylate
Reverse
β-oxidationchain-extension core
β-oxidationchain-extension core
Explore the resource
Find a connection, then follow its evidence.
Search organisms, strains, assemblies, genes, enzymes, metabolites and orthogroups.Research-driven knowledgebase