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FUNCTIONAL ORTHOLOGY EXPLORER
Interactively inspect annotation-supported markers, orthogroups, and pathway-rule coverage across curated genomes. Genomic presence is not evidence of expression or demonstrated MCFA production.
Search by organism or versioned assembly accession and open its evidence record.
Focus on a named enzyme marker or MCFA pathway module.
Expand the heatmap to compare marker copy-number patterns.
Distinguish annotations, reviewed candidates, and pathway assessments.
50 genomes currently visible
Organism names are shown first; assembly accessions remain available as secondary identifiers. The preview is limited to the first 100 matching genomes.
| Organism and assembly | Detected markers | Pathway assessments |
|---|---|---|
Acetobacterium carbinolicumGCA_047456275.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMadhEHMMcoatHMM×2etfAHMMetfBHMMfabFHMMfabGHMM×2fabZHMMlctPHMMrnfAHMMrnfBHMMrnfCHMM×2rnfDHMMrnfEHMM | reversebetaoxidationcore 0/4bcdetfmodule 2/3rnfcomplex 5/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 6/8 |
Acetobacterium malicum subsp. dehalogenans DSM 11527GCA_047456285.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×2etfAHMM×2etfBHMM×2fabFHMMfabGHMMfabKHMMfabZHMMlctPHMMrnfAHMM×2rnfBHMM×2rnfCHMM×3rnfDHMM×2rnfEHMM×2rnfGHMMthlHMMbcdHMM | reversebetaoxidationcore 2/4bcdetfmodule 3/3rnfcomplex 6/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Acetobacterium wieringaeGCA_023700225.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×2crtHMMetfAHMMetfBHMMfabFHMMfabGHMMfabKHMMfabZHMMhbdHMMlctPHMMrnfAHMM×2rnfBHMM×2rnfCHMM×3rnfDHMM×2rnfEHMM×2rnfGHMM×2 | reversebetaoxidationcore 2/4bcdetfmodule 2/3rnfcomplex 6/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Acetobacterium woodii DSM 1030GCA_000247605.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMadhEHMMcoatHMM×2etfAHMMetfBHMMfabFHMMfabGHMMfabZHMMlctPHMMrnfAHMMrnfBHMMrnfCHMM×2rnfDHMMrnfEHMM | reversebetaoxidationcore 0/4bcdetfmodule 2/3rnfcomplex 5/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 6/8 |
Anaerostipes caccaeGCA_020181435.1Complete Genome | accBHMMcoatHMM×2crtHMMetfAHMMetfBHMM×2fabDHMMfabFHMMfabGHMMfabZHMMlctPHMMrnfAHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMMbcdHMM | reversebetaoxidationcore 2/4bcdetfmodule 3/3rnfcomplex 5/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 4/8 |
Anaerostipes caccae L1-92GCA_025146005.1Complete Genome | accBHMMcoatHMM×2crtHMMetfAHMMetfBHMM×2fabDHMMfabFHMMfabGHMMfabZHMMlctPHMMrnfAHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMMbcdHMM | reversebetaoxidationcore 2/4bcdetfmodule 3/3rnfcomplex 5/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 4/8 |
Anaerostipes hadrusGCA_030864025.1Complete Genome | accBHMM×2accCHMMcoatHMM×2crtHMMetfAHMM×2etfBHMM×2fabDHMMfabFHMMfabGHMMfabZHMMlctPHMMrnfAHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMMrnfGHMM | reversebetaoxidationcore 1/4bcdetfmodule 2/3rnfcomplex 6/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 5/8 |
Anaerostipes hadrus ATCC 29173 = JCM 17467GCA_030296915.1Complete Genome | accBHMM×2accCHMMcoatHMM×2crtHMMetfAHMM×2etfBHMM×2fabDHMMfabFHMMfabGHMMfabZHMMlctPHMMrnfAHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMMrnfGHMM | reversebetaoxidationcore 1/4bcdetfmodule 2/3rnfcomplex 6/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 5/8 |
Anaerostipes rhamnosivoransGCA_005280655.1Complete Genome | accBHMMcoatHMM×2crtHMMetfAHMMetfBHMM×2fabDHMMfabFHMMfabGHMMfabZHMMlctPHMMrnfAHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMMrnfGHMM | reversebetaoxidationcore 1/4bcdetfmodule 2/3rnfcomplex 6/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 4/8 |
Bordetella aviumGCA_034424645.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×2fabFHMMfabGHMMfabIHMM×2fabZHMMhbdHMM×2thlHMM×4 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella avium 197NGCA_000070465.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×2fabFHMMfabGHMMfabIHMM×2fabZHMMhbdHMM×2thlHMM×4 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella bronchialisGCA_001676705.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×3fabFHMMfabGHMM×2fabIHMMfabZHMMthlHMM×5 | reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella bronchiseptica 253GCA_000318015.1Complete Genome | accBHMM×3accAHMMaccCHMM×3accDHMMcoatHMM×4fabFHMMfabGHMM×3fabIHMM×2fabZHMMhbdHMM×2thlHMM×8 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella bronchiseptica MO149GCA_000317955.1Complete Genome | accAHMMaccBHMM×2accCHMM×3accDHMMcoatHMM×4fabFHMMfabGHMM×2fabIHMM×2fabZHMMhbdHMMthlHMM×8 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella bronchiseptica RB50GCA_000195675.1Complete Genome | accBHMM×2accAHMMaccCHMM×3accDHMMcoatHMM×4fabFHMMfabGHMM×3fabIHMM×2fabZHMMhbdHMM×2thlHMM×9 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella flabilisGCA_001676725.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×4fabFHMMfabGHMM×2fabIHMMfabZHMMthlHMM×6 | reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella genomosp. 13GCA_002119665.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×2fabFHMMfabGHMMfabIHMMfabZHMMhbdHMMthlHMM×6 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella genomosp. 6GCA_002119705.1Complete Genome | fabIHMM×2fabZHMMhbdHMM×2thlHMM×9accBHMM×2accAHMMaccCHMM×3accDHMMcoatHMM×4fabFHMMfabGHMM×3 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella genomosp. 8GCA_002119685.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×3fabFHMMfabGHMM×2fabIHMMfabZHMMthlHMM×5 | reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella genomosp. 9GCA_002119725.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×4fabFHMMfabGHMM×2fabIHMMfabZHMMthlHMM×4 | reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella holmesiiGCA_020735985.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×2fabFHMMfabGHMMfabIHMMfabZHMMhbdHMMthlHMM×3 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella holmesii 44057GCA_000765395.1Complete Genome | accBHMMaccAHMMaccCHMMaccDHMMcoatHMM×2fabFHMMfabGHMMfabHHMMfabIHMMfabZHMMthlHMM×3 | reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 7/8 |
Bordetella holmesii ATCC 51541GCA_048296725.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×2fabFHMMfabGHMMfabIHMMfabZHMMhbdHMMthlHMM×3 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella holmesii F627GCA_000341465.2Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×2fabFHMMfabGHMMfabIHMMfabZHMMhbdHMMthlHMM×3 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella holmesii H558GCA_000341485.2Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×2fabFHMMfabGHMMfabIHMMfabZHMMhbdHMMthlHMM×3 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella parapertussisGCA_020735925.1Complete Genome | accAHMMaccBHMM×2accCHMM×2accDHMMcoatHMM×4fabFHMMfabGHMM×2fabIHMM×2fabZHMMhbdHMM×2thlHMM×8 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella parapertussis 12822GCA_000195695.1Complete Genome | accAHMMaccBHMM×2accCHMM×2accDHMMcoatHMM×4fabFHMMfabGHMM×2fabIHMM×2fabZHMMhbdHMM×2thlHMM×8 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella parapertussis Bpp5GCA_000317935.1Complete Genome | accAHMMaccBHMM×2accCHMM×2accDHMMcoatHMM×3fabFHMMfabGHMM×3fabIHMM×2fabZHMMhbdHMMthlHMM×7 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella pertussisGCA_004008975.1Complete Genome | accAHMMaccBHMM×2accCHMM×2accDHMMcoatHMM×3fabFHMMfabGHMMfabIHMM×2fabZHMMhbdHMMthlHMM×4 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella pertussis 137GCA_000812165.1Complete Genome | accAHMMaccBHMM×2accCHMM×2accDHMMcoatHMM×3fabFHMMfabGHMMfabIHMM×2fabZHMMhbdHMMthlHMM×5 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella pertussis 18323GCA_000306945.1Complete Genome | accAHMMaccBHMM×2accCHMM×2accDHMMcoatHMM×2fabFHMMfabGHMMfabIHMM×2fabZHMMhbdHMMthlHMM×6 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella pertussis B1917GCA_000193595.3Complete Genome | accAHMMaccBHMM×2accCHMM×2accDHMMcoatHMM×3fabFHMMfabGHMMfabIHMM×2fabZHMMhbdHMMthlHMM×4 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella pertussis B1920GCA_000193615.3Complete Genome | accAHMMaccBHMM×2accCHMM×2accDHMMcoatHMM×3fabFHMMfabGHMMfabIHMM×2fabZHMMhbdHMMthlHMM×4 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella pertussis CSGCA_023612135.1Complete Genome | accAHMMaccBHMM×2accCHMM×2accDHMMcoatHMM×3fabFHMMfabGHMMfabIHMM×2fabZHMMhbdHMMthlHMM×4 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella pertussis Tohama IGCA_004794295.1Complete Genome | accAHMMaccBHMM×2accCHMM×2accDHMMcoatHMM×3fabFHMMfabGHMMfabIHMM×2fabZHMMhbdHMMthlHMM×4 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella petriiGCA_000067205.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×7fabFHMMfabGHMM×2fabIHMMfabZHMMhbdHMMthlHMM×8 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella pseudohinziiGCA_001698185.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×3fabFHMMfabGHMMfabIHMMfabZHMMhbdHMM×2thlHMM×5 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella sp. 2513F-2GCA_054642735.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×4fabFHMMfabGHMMfabIHMMfabZHMMhbdHMMthlHMM×5 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella sp. H567GCA_001704295.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×3fabFHMMfabGHMM×2fabIHMMfabZHMMthlHMM×4 | reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella sp. J329GCA_004006215.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMMfabFHMMfabGHMMfabIHMM×2fabZHMMlctPHMMthlHMM×4 | reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella sp. LUAb4GCA_021325795.2Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×4fabFHMMfabGHMM×2fabIHMMfabZHMM×2hbdHMMthlHMM×4 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella sp. MIP270_01_BMSGCF_054958705.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×5fabFHMMfabGHMMfabIHMMfabZHMMhbdHMMthlHMM×6 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Bordetella trematumGCA_011386965.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcoatHMM×2fabFHMMfabGHMM×2fabIHMMfabZHMMhbdHMMthlHMM×7 | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Caproicibacter fermentansGCA_014303955.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcrtHMMetfAHMMetfBHMM×2fabFHMMfabGHMMfabKHMMfabZHMMlctPHMMrnfAHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMMrnfGHMMbcdHMM | reversebetaoxidationcore 2/4bcdetfmodule 3/3rnfcomplex 6/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Caproicibacter sp. BJN0012GCA_035986805.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMbcdHMM×2crtHMM×3etfAHMM×2etfBHMM×3fabFHMMfabGHMMfabZHMMhbdHMM×2lctPHMM×2rnfAHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMMrnfGHMMthlHMM | reversebetaoxidationcore 4/4bcdetfmodule 3/3rnfcomplex 6/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8 |
Caproicibacterium amylolyticumGCA_014467055.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcrtHMMfabFHMMfabGHMMfabKHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMMrnfGHMM | reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 5/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 5/8 |
Caproicibacterium argilliputeiGCA_029211325.2Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcrtHMMfabFHMMfabGHMMfabKHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMM | reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 4/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 5/8 |
Caproicibacterium lactatifermentansGCA_013315815.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcrtHMMetfAHMMetfBHMMfabFHMMfabGHMMfabKHMMfabZHMMlctPHMMrnfAHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMMbcdHMM | lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8reversebetaoxidationcore 2/4bcdetfmodule 3/3rnfcomplex 5/6 |
Caproicibacterium sp. BJN0003GCA_026314295.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcrtHMMfabFHMMfabGHMMrnfAHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMMrnfGHMMthlHMM | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 6/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 5/8 |
Caproicibacterium sp. NSD3GCF_053613275.1Complete Genome | accAHMMaccBHMMaccCHMMaccDHMMcrtHMMfabFHMMfabGHMMrnfAHMMrnfBHMMrnfCHMMrnfDHMMrnfEHMMrnfGHMMthlHMM | reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 6/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 5/8 |
No genomes match the current filters.
Enter a marker gene to narrow the orthogroup menu. Select an orthogroup to inspect its complete imported protein records.
Absence may reflect incomplete assemblies or annotations. Orthogroup membership is supporting evidence only; unannotated orthologues are not automatically promoted to confirmed enzyme calls. Pathway completeness is marker-rule completeness and is not a flux or thermodynamic prediction.