Assembly
ASM19190v1
BioProject PRJNA50455 · BioSample SAMN02603410
GENOME-RESOLVED EVIDENCE
GCA_000191905.1
Clostridium acetobutylicum · Complete Genome
View versioned NCBI assembly →
Quality metadata
Genome size 4132226 bp · GC 31.000%
Completeness 97.840% · contamination 0.930%
Pathway marker completeness
| Module | Markers | Fraction | Call |
|---|---|---|---|
| bcd_etf_module | 1/3 | 0.333 | Partial/absent |
| ethanol_entry_support | 0/1 | 0.000 | Partial/absent |
| fatty_acid_biosynthesis_core | 3/8 | 0.375 | Partial/absent |
| lactate_entry_support | 1/2 | 0.500 | Partial/absent |
| reverse_beta_oxidation_core | 4/4 | 1.000 | Complete marker set |
| rnf_complex | 0/6 | 0.000 | Partial/absent |
Detected markers
| Marker | Function | Copies |
|---|---|---|
| accA | acetyl-CoA carboxylase carboxyltransferase alpha | 1 |
| accD | acetyl-CoA carboxylase carboxyltransferase beta | 1 |
| fabG | 3-oxoacyl-ACP reductase | 1 |
| ldh | L-lactate dehydrogenase | 1 |
| bcd | butyryl-CoA dehydrogenase | 1 |
| crt | crotonase/enoyl-CoA hydratase | 3 |
| hbd | 3-hydroxybutyryl-CoA dehydrogenase | 1 |
| thl | acetyl-CoA acetyltransferase/thiolase | 2 |
| coat | butyrate/acetoacetate CoA-transferase | 2 |
Profile-HMM marker predictions
Approved candidates and review records are genomic predictions, not evidence of expression or MCFA production. Excluded matches remain visible for audit.
| Marker / protein | Confidence | Review status | Score / coverage | Supporting evidence |
|---|---|---|---|---|
| No profile-HMM predictions for this assembly. | ||||
Protein-level evidence
| Gene | Protein | Orthogroup | Coordinates | Annotation |
|---|---|---|---|---|
| ldhCEA_G0273 | ADZ19314.1 | OG0000131 | CP002118.1:298767–299708 + | L-lactate dehydrogenase [Clostridium acetobutylicum EA 2018] |
| ctfaCEA_P0161 | ADZ22944.1 | OG0000158 | CP002119.1:178459–179115 + | Butyrate-acetoacetate COA-transferase subunit A (plasmid) [Clostridium acetobutylicum EA 2018] |
| ctfbCEA_P0162 | ADZ22945.1 | OG0000158 | CP002119.1:179117–179782 + | Butyrate-acetoacetate COA-transferase subunit B (plasmid) [Clostridium acetobutylicum EA 2018] |
| hbdCEA_G2716 | ADZ21753.1 | OG0000229 | CP002118.1:2830987–2831835 - | 3-hydroxybutyryl-CoA dehydrogenase [Clostridium acetobutylicum EA 2018] |
| thlCEA_G2880 | ADZ21917.1 | OG0000234 | CP002118.1:3005220–3006398 - | acetyl-CoA acetyltransferase [Clostridium acetobutylicum EA 2018] |
| thilCEA_P0077 | ADZ22860.1 | OG0000234 | CP002119.1:82040–83218 - | acetyl-CoA acetyltransferase (plasmid) [Clostridium acetobutylicum EA 2018] |
| accDCEA_G3576 | ADZ22613.1 | OG0000403 | CP002118.1:3769264–3770121 - | Acetyl-CoA carboxylase beta subunit [Clostridium acetobutylicum EA 2018] |
| accACEA_G3575 | ADZ22612.1 | OG0000885 | CP002118.1:3768423–3769247 - | Acetyl-CoA carboxylase alpha subunit [Clostridium acetobutylicum EA 2018] |
| bcdCEA_G2719 | ADZ21756.1 | OG0001311 | CP002118.1:2833767–2834906 - | Butyryl-CoA dehydrogenase [Clostridium acetobutylicum EA 2018] |
| fabGCEA_G3466 | ADZ22503.1 | OG0004652 | CP002118.1:3661048–3661836 + | 3-oxoacyl-acyl carrier protein reductase [Clostridium acetobutylicum EA 2018] |
| crtCEA_G2027 | ADZ21064.1 | OG0014900 | CP002118.1:2124954–2125643 - | Enoyl-CoA hydratase [Clostridium acetobutylicum EA 2018] |
| crtCEA_G2031 | ADZ21068.1 | OG0014902 | CP002118.1:2127245–2127982 - | Enoyl-CoA hydratase [Clostridium acetobutylicum EA 2018] |
| fadBCEA_G0571 | ADZ19610.1 | OG0018950 | CP002118.1:645222–645413 + | Enoyl-CoA hydratase [Clostridium acetobutylicum EA 2018] |
These are genomic annotation predictions. Experimental activity, expression and metabolite production require separate evidence.