SPECIES · STRAIN AND FUNCTION PROFILE

Caproicibacterium lactatifermentans

Validated caproate producer Primary fermentation · High Reverse β-oxidation chain elongation · High Energy conservation · High

Role labels distinguish demonstrated caproate production from community association; validate at strain level before causal interpretation.

1strain profiles

1assemblies

6MCFA marker genes

17%strain metadata coverage

Name, taxonomy and strain identifiers

Curation status: Exact match imported · Culture collection identifier · checked 2026-07-29. Exact strain-level match; curated BacDive fields imported.

Taxonomic record

Scientific name: Caproicibacterium lactatifermentans
Rank: species
NCBI Taxonomy: 2666138
Database role: Validated caproate producer

LBM19010 Type strain

Full name: Caproicibacterium lactatifermentans Wang et al. 2022
Culture collections: GDMCC 1.1627, JCM 33782
History: Not curated
BacDive: Strain 166884

Morphology and observable traits

Strain	Gram stain	Cell shape	Motility	Spore formation	Colony morphology
LBM19010	Not curated	Not curated	Not curated	Not curated	Not curated

Culture and growth conditions

Strain	Medium	Temperature	pH	Atmosphere/result
No cultivation record for LBM19010.

Documented condition ranges

Profile	pH	Temperature	Electron donors	Substrates/reactor
Documented growth/production range	4.50–7.50; optimum 5.25	20.00–40.00 °C; optimum 35.00	lactate, glucose	hexoses, disaccharides, starch, lactate; batch; strain-dependent continuous culture evidence

Physiology and metabolism

Documented substrates and products

Only approved assertions are shown. Results may be strain- and condition-specific.

Relationship	Compound/source term	Evidence	Confidence	Condition
Product	butyrate	Curator assertionExisting mcfaKB curator phenotype summaries	0.800	Not recorded
Product	caproate	Curator assertionExisting mcfaKB curator phenotype summaries	0.800	Not recorded
Substrate	glucose	Curator assertionExisting mcfaKB curator phenotype summaries	0.800	Not recorded
Substrate	lactate	Curator assertionExisting mcfaKB curator phenotype summaries	0.800	Not recorded

Predicted metabolic capabilities

Genome-derived hypotheses requiring review—not demonstrated substrates or products.

Capability	Basis/status	Confidence	Assemblies	Limitation
No genome-derived capabilities available.

Isolation, environment and safety

Strain	Isolation source	Category/location	Oxygen tolerance	Biosafety	GC content
LBM19010	Not curated	—	Not curated	Not curated	—%

Sequence information

Genome assemblies

Accession	Source	Level	Size/GC	Quality	BioProject
GCA_013315815.1	NCBI GenBank	Complete Genome	1989979 bp / 50.500%	—% complete; —% contamination	PRJNA588583

Marker and ribosomal sequences

Strain	Type	Accession	Length	Description
LBM19010	16S rRNA	MT580120	1363 bp	Caproicibacterium lactatifermentans strain LBM19010 16S ribosomal RNA gene, partial sequence

MCFA pathways and genes

Reverse β-oxidation (chain elongation)1 of 5 functions20%20%

Fatty acid biosynthesis (FAS II)1 of 7 functions14%14%

Show 6 annotation-derived MCFA genes

Gene	Locus	Function	Protein	Orthogroup
hbd	GJQ69_04200	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	QKN23749.1	—
accB	GJQ69_04985	Acetyl-CoA carboxylase (6.4.1.2)	QKN23889.1	—
accC	GJQ69_04995	Acetyl-CoA carboxylase (6.4.1.2)	QKN23891.1	—
acc	GJQ69_05000	Acetyl-CoA carboxylase (6.4.1.2)	QKN23892.1	—
acc	GJQ69_05005	Acetyl-CoA carboxylase (6.4.1.2)	QKN23893.1	—
ldh	GJQ69_09295	L-lactate dehydrogenase (1.1.1.27)	QKN24832.1	—

Curator-approved marker pathway assessments

These summaries use approved candidate predictions only and update after every review decision.

Assembly	Pathway rule	Approved markers	Status
GCA_013315815.1	bcd_etf_module	3 / 3	Complete
GCA_013315815.1	ethanol_entry_support	0 / 1	Incomplete
GCA_013315815.1	fatty_acid_biosynthesis_core	6 / 8	Incomplete
GCA_013315815.1	lactate_entry_support	1 / 2	Incomplete
GCA_013315815.1	reverse_beta_oxidation_core	2 / 4	Incomplete
GCA_013315815.1	rnf_complex	5 / 6	Incomplete

Profile-HMM marker predictions

Approved candidates and unresolved review calls are genomic hypotheses, not evidence of expression or MCFA production.

Marker	Assembly / protein	Confidence and status	Support	Review history
accAacetyl-CoA carboxylase carboxyltransferase alpha	GCA_013315815.1WP_086035778.1 · acetyl-CoA carboxylase carboxyltransferase subunit alpha	High · Approved candidate	OG0001120	0 decisionsstrong profile and bridge orthogroup support
accBacetyl-CoA carboxylase biotin carboxyl carrier protein	GCA_013315815.1WP_086035782.1 · acetyl-CoA carboxylase biotin carboxyl carrier protein	Medium · Approved candidate	gene_symbol	0 decisionsstrong profile plus independent annotation support: gene_symbol
accCacetyl-CoA carboxylase biotin carboxylase	GCA_013315815.1WP_086035780.1 · acetyl-CoA carboxylase biotin carboxylase subunit	Medium · Approved candidate	gene_symbol	0 decisionsstrong profile plus independent annotation support: gene_symbol
accDacetyl-CoA carboxylase carboxyltransferase beta	GCA_013315815.1WP_086035779.1 · acetyl-CoA carboxylase, carboxyltransferase subunit beta	High · Approved candidate	OG0000844gene_symbol	0 decisionsstrong profile and bridge orthogroup support; annotation support: gene_symbol
bcdbutyryl-CoA dehydrogenase	GCA_013315815.1WP_086035133.1 · acyl-CoA dehydrogenase	Medium · Approved candidate	bcd_etfAB_neighborhood	1 decisionContext-supported Bcd candidate: calibrated profile hit co-localized with independently approved EtfA and EtfB within six CDS positions.
bcdbutyryl-CoA dehydrogenase	GCA_013315815.1WP_174193440.1 · acyl-CoA dehydrogenase family protein	Medium · Needs review		0 decisionsretain confidence tier and orthogroup-support fields during import
crtcrotonase/enoyl-CoA hydratase	GCA_013315815.1WP_086035923.1 · enoyl-CoA hydratase-related protein	High · Approved candidate	OG0002531specific_product_name	0 decisionsstrong profile and bridge orthogroup support; annotation support: specific_product_name
etfAelectron transfer flavoprotein alpha subunit	GCA_013315815.1WP_086035132.1 · electron transfer flavoprotein subunit alpha/FixB family protein	High · Approved candidate	OG0001385	0 decisionsstrong profile and bridge orthogroup support
etfBelectron transfer flavoprotein beta subunit	GCA_013315815.1WP_086035131.1 · electron transfer flavoprotein subunit beta/FixA family protein	High · Approved candidate	OG0001139	0 decisionsstrong profile and bridge orthogroup support
fabF3-oxoacyl-ACP synthase II	GCA_013315815.1WP_174193146.1 · beta-ketoacyl-ACP synthase II	Medium · Approved candidate	gene_symbol	0 decisionsstrong profile plus independent annotation support: gene_symbol
fabG3-oxoacyl-ACP reductase	GCA_013315815.1WP_086035784.1 · 3-oxoacyl-[acyl-carrier-protein] reductase	High · Approved candidate	OG0000008gene_symbol	0 decisionsstrong profile and bridge orthogroup support; annotation support: gene_symbol
fabG3-oxoacyl-ACP reductase	GCA_013315815.1WP_086036616.1 · elongation factor P 5-aminopentanone reductase	Medium · Needs review		0 decisionsextreme per-proteome copy number; profile alone is not function-specific
fabG3-oxoacyl-ACP reductase	GCA_013315815.1WP_086036673.1 · SDR family NAD(P)-dependent oxidoreductase	Medium · Needs review	OG0000242	0 decisionsextreme per-proteome copy number; profile alone is not function-specific
fabG3-oxoacyl-ACP reductase	GCA_013315815.1WP_086036403.1 · SDR family NAD(P)-dependent oxidoreductase	Medium · Needs review	OG0000242	0 decisionsextreme per-proteome copy number; profile alone is not function-specific
fabH3-oxoacyl-ACP synthase III	GCA_013315815.1WP_174193135.1 · beta-ketoacyl-ACP synthase III	Medium · Needs review		0 decisionsno bridge-supported orthogroup; require domain, motif, or neighborhood confirmation
fabKenoyl-ACP reductase FabK	GCA_013315815.1WP_174193144.1 · enoyl-[acyl-carrier-protein] reductase FabK	Medium · Approved candidate	gene_symbol	0 decisionsstrong profile plus independent annotation support: gene_symbol
fabLenoyl-ACP reductase FabL	GCA_013315815.1WP_086035784.1 · 3-oxoacyl-[acyl-carrier-protein] reductase	Medium · Needs review		0 decisionsextreme per-proteome copy number; profile alone is not function-specific
fabLenoyl-ACP reductase FabL	GCA_013315815.1WP_086036616.1 · elongation factor P 5-aminopentanone reductase	Medium · Needs review		0 decisionsextreme per-proteome copy number; profile alone is not function-specific
fabZ3-hydroxyacyl-ACP dehydratase	GCA_013315815.1WP_086035781.1 · 3-hydroxyacyl-ACP dehydratase FabZ	Medium · Approved candidate	OG0000074gene_symbol	0 decisionsstrong profile plus independent annotation support: gene_symbol
hbd3-hydroxybutyryl-CoA dehydrogenase	GCA_013315815.1WP_174193045.1 · 3-hydroxybutyryl-CoA dehydrogenase	Medium · Needs review		0 decisionsretain confidence tier and orthogroup-support fields during import
lctPL-lactate permease	GCA_013315815.1WP_236849684.1 · L-lactate permease	High · Approved candidate	OG0000731	0 decisionsstrong profile and bridge orthogroup support
ldhL-lactate dehydrogenase	GCA_013315815.1WP_086036714.1 · L-lactate dehydrogenase	Medium · Needs review		0 decisionsretain confidence tier and orthogroup-support fields during import
rnfARnf complex subunit A	GCA_013315815.1WP_174193065.1 · electron transport complex protein RnfA	High · Approved candidate	OG0001169	0 decisionsstrong profile and bridge orthogroup support
rnfBRnf complex subunit B	GCA_013315815.1WP_086035903.1 · RnfABCDGE type electron transport complex subunit B	High · Approved candidate	OG0001404	0 decisionsstrong profile and bridge orthogroup support
rnfCRnf complex subunit C	GCA_013315815.1WP_086035899.1 · electron transport complex subunit RsxC	High · Approved candidate	OG0001114	0 decisionsstrong profile and bridge orthogroup support
rnfDRnf complex subunit D	GCA_013315815.1WP_086035900.1 · RnfABCDGE type electron transport complex subunit D	High · Approved candidate	OG0001182	0 decisionsstrong profile and bridge orthogroup support
rnfERnf complex subunit E	GCA_013315815.1WP_174193067.1 · electron transport complex subunit RsxE	High · Approved candidate	OG0001153	0 decisionsstrong profile and bridge orthogroup support
thlacetyl-CoA acetyltransferase/thiolase	GCA_013315815.1WP_086035924.1 · acetyl-CoA C-acetyltransferase	Medium · Needs review		0 decisionsretain confidence tier and orthogroup-support fields during import

Literature and provenance

Study	DOI	Public data
Revealing glucose- and lactate-based chain elongation in Caproicibacterium lactatifermentans	10.1128/spectrum.01723-22	—

Profile evidence

BacDive strain record 166884: Caproicibacterium lactatifermentans LBM19010 — Curator assertion

External databases can change. mcfaKB records source links and separates experimentally reported, curator-entered and predicted information.