SPECIES · STRAIN AND FUNCTION PROFILE

Clostridium butyricum

Reported/putative producer

Imported from the NCBI assembly data report; MCFA production is not implied.

1strain profiles

22assemblies

290MCFA marker genes

67%strain metadata coverage

Name, taxonomy and strain identifiers

Curation status: Exact match imported · Genome assembly accession · checked 2026-07-29. Exact strain-level match; curated BacDive fields imported.

Taxonomic record

Scientific name: Clostridium butyricum
Rank: species
NCBI Taxonomy: Not resolved at this level
Database role: Reported/putative producer

Rowett Type strain

Full name: Clostridium butyricum Prazmowski 1880
Culture collections: DSM 10702, ATCC 19398, IAM 14194, IFO 13949, JCM 1391, NBRC 13949, NCIMB 7423, NCTC 7423, VPI 3266, BCRC 11665, CCUG 4217, CECT 361, CIP 103309, CIP 109397, HAMBI 482, KCTC 1786, KCTC 1871, LMG 1217, NCFB 1713, VTT E-97426
History: Not curated
BacDive: Strain 2563

Morphology and observable traits

Strain	Gram stain	Cell shape	Motility	Spore formation	Colony morphology
Rowett	Not curated	Not curated	Not curated	Not curated	Not curated

Culture and growth conditions

Strain	Medium	Temperature	pH	Atmosphere/result
Rowett	CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110)DSMZ Medium 110 · Name: CHOPPED MEAT MEDIUM WITH CARBOHYDRATES (DSMZ Medium 110) Composition: Ground beef 500.0 g/l Casitone 30.0 g/l Agar 15.0 g/l K2HPO4 5.0 g/l Yeast extract 5.0 g/l D-Glucose 4.0 g/l Starch 1.0 g/l Maltose 1.0 g/l Cellobiose 1.0 g/l L-Cysteine HCl 0.5 g/l Ethanol 0.19 g/l Vitamin K3 0.05 g/l Hemin 0.005 g/l Sodium resazurin 0.0005 g/l Vitamin K1 NaOH Distilled water	37.00 °C	—	anaerobe · yes
Rowett	MEDIUM 20 - for Anaerobic bacteria · Agar (15.000 g);Glucose (5.000 g);Yeast extract (20.000 g);Tryptone (30.000 g);Cysteine hydrochloride (0.500 g);distilled water (1000.000 ml);Hemin solution -M00149 (25.000 ml)	37.00 °C	—	anaerobe · yes
Rowett	PYG MEDIUM (MODIFIED) (DSMZ Medium 104)DSMZ Medium 104 · Name: PYG MEDIUM (MODIFIED) (DSMZ Medium 104) Composition: Yeast extract 10.0 g/l Peptone 5.0 g/l Trypticase peptone 5.0 g/l Beef extract 5.0 g/l Glucose 5.0 g/l L-Cysteine HCl x H2O 0.5 g/l NaHCO3 0.4 g/l NaCl 0.08 g/l K2HPO4 0.04 g/l KH2PO4 0.04 g/l MgSO4 x 7 H2O 0.02 g/l CaCl2 x 2 H2O 0.01 g/l Hemin 0.005 g/l Ethanol 0.0038 g/l Resazurin 0.001 g/l Tween 80 Vitamin K1 NaOH Distilled water	37.00 °C	—	anaerobe · yes
Rowett	COLUMBIA BLOOD MEDIUM (DSMZ Medium 693)DSMZ Medium 693 · Name: COLUMBIA BLOOD MEDIUM (DSMZ Medium 693) Composition: Defibrinated sheep blood 50.0 g/l Columbia agar base	37.00 °C	—	anaerobe · yes

Documented condition ranges

Profile	pH	Temperature	Electron donors	Substrates/reactor
BacDive documented cultivation conditions	?–?; optimum ?	37.00–37.00 °C; optimum ?	Not curated	—; culture-collection cultivation
Species-level documented cultivation conditions	?–?; optimum ?	30.00–37.00 °C; optimum ?	Not curated	—; species-level culture records

Physiology and metabolism

Documented substrates and products

Only approved assertions are shown. Results may be strain- and condition-specific.

Relationship	Compound/source term	Evidence	Confidence	Condition
No approved strain-level phenotype assertions yet.

Predicted metabolic capabilities

Genome-derived hypotheses requiring review—not demonstrated substrates or products.

Capability	Basis/status	Confidence	Assemblies	Limitation
reverse beta-oxidation potential	Genomic prediction · Needs review	0.600	GCA_006742065.1	Complete marker-rule set; not evidence of expression, flux, or product formation.
lactate transport potential	Genomic prediction · Needs review	0.450	GCA_001746555.1, GCA_030758275.1, GCA_013112415.1, GCA_001646605.1, GCA_041937605.1, GCA_014131795.1, GCA_049991395.1, GCA_006742065.1, GCA_001456065.2, GCA_050366995.1, GCA_024399875.1, GCA_009650315.1, GCA_052805695.1, GCA_001886875.1, GCA_027627495.1, GCA_055694005.1, GCA_001465175.1, GCA_009650335.1, GCA_057321305.1, GCA_030389005.1, GCA_005145085.1, GCA_018140655.1	Transporter annotation supports uptake potential but not utilization.
lactate metabolism potential	Genomic prediction · Needs review	0.400	GCA_024399875.1, GCA_027627495.1, GCA_030389005.1, GCA_030758275.1, GCA_041937605.1, GCA_049991395.1, GCA_050366995.1, GCA_052805695.1, GCA_055694005.1, GCA_057321305.1, GCA_018140655.1, GCA_001456065.2, GCA_001465175.1, GCA_001646605.1, GCA_001746555.1, GCA_001886875.1, GCA_005145085.1, GCA_006742065.1, GCA_009650315.1, GCA_009650335.1, GCA_013112415.1, GCA_014131795.1	LDH presence does not establish reaction direction or growth on lactate.
ethanol metabolism potential	Genomic prediction · Needs review	0.400	GCA_024399875.1, GCA_027627495.1, GCA_030389005.1, GCA_030758275.1, GCA_041937605.1, GCA_049991395.1, GCA_050366995.1, GCA_052805695.1, GCA_055694005.1, GCA_057321305.1, GCA_018140655.1, GCA_001456065.2, GCA_001465175.1, GCA_001646605.1, GCA_001746555.1, GCA_005145085.1, GCA_009650315.1, GCA_009650335.1, GCA_013112415.1, GCA_014131795.1	AdhE can participate in ethanol production or consumption depending on physiology.

Isolation, environment and safety

Strain	Isolation source	Category/location	Oxygen tolerance	Biosafety	GC content
Rowett	Not curated	—	anaerobe	2Risk group (German classification)	28.000%

Sequence information

Genome assemblies

Accession	Source	Level	Size/GC	Quality	BioProject
GCA_018140655.1	NCBI GenBank	Complete Genome	4488390 bp / 29.000%	94.470% complete; 2.750% contamination	PRJNA722306
GCA_001456065.2	NCBI GenBank	Complete Genome	4627894 bp / 28.500%	95.470% complete; 2.460% contamination	PRJNA304074
GCA_001465175.1	NCBI GenBank	Complete Genome	4618327 bp / 28.500%	94.270% complete; 1.240% contamination	PRJNA303063
GCA_001646605.1	NCBI GenBank	Complete Genome	4597202 bp / 28.500%	95.940% complete; 1.620% contamination	PRJNA314015
GCA_001746555.1	NCBI GenBank	Complete Genome	4463546 bp / 28.500%	—% complete; —% contamination	PRJNA327147
GCA_001886875.1	NCBI GenBank	Complete Genome	4639914 bp / 28.500%	97.210% complete; 1.510% contamination	PRJNA301981
GCA_005145085.1	NCBI GenBank	Complete Genome	4636588 bp / 29.000%	95.890% complete; 2.400% contamination	PRJNA534376
GCA_006742065.1	NCBI GenBank	Complete Genome	4705096 bp / 28.500%	96.970% complete; 2.770% contamination	PRJDB8042
GCA_009650315.1	NCBI GenBank	Complete Genome	4746849 bp / 29.000%	96.390% complete; 2.700% contamination	PRJNA498210
GCA_009650335.1	NCBI GenBank	Complete Genome	4746782 bp / 29.000%	96.560% complete; 2.700% contamination	PRJNA498210
GCA_013112415.1	NCBI GenBank	Complete Genome	4630815 bp / 28.500%	96.070% complete; 2.400% contamination	PRJNA630842
GCA_014131795.1	NCBI GenBank	Complete Genome	4705596 bp / 28.500%	96.970% complete; 2.770% contamination	PRJNA544389
GCA_024399875.1	NCBI GenBank	Complete Genome	4697138 bp / 28.500%	95.390% complete; 2.480% contamination	PRJNA632418
GCA_027627495.1	NCBI GenBank	Complete Genome	4625068 bp / 28.500%	96.160% complete; 2.400% contamination	PRJNA913558
GCA_030389005.1	NCBI GenBank	Complete Genome	4630814 bp / 28.500%	96.160% complete; 2.400% contamination	PRJNA987805
GCA_030758275.1	NCBI GenBank	Complete Genome	4609089 bp / 28.500%	95.940% complete; 1.620% contamination	PRJNA1003819
GCA_041937605.1	NCBI GenBank	Complete Genome	4630768 bp / 28.500%	95.760% complete; 2.400% contamination	PRJNA1158993
GCA_049991395.1	NCBI GenBank	Complete Genome	4817503 bp / 29.000%	96.160% complete; 2.750% contamination	PRJNA1252985
GCA_050366995.1	NCBI GenBank	Complete Genome	4708966 bp / 29.000%	96.180% complete; 2.710% contamination	PRJNA1259948
GCA_052805695.1	NCBI GenBank	Complete Genome	4611195 bp / 29.000%	95.580% complete; 1.620% contamination	PRJNA1328834
GCA_055694005.1	NCBI GenBank	Complete Genome	4444008 bp / 29.000%	86.700% complete; 3.370% contamination	PRJNA1371646
GCA_057321305.1	NCBI GenBank	Complete Genome	4665638 bp / 29.000%	83.940% complete; 4.660% contamination	PRJNA1114922

Marker and ribosomal sequences

Strain	Type	Accession	Length	Description
Rowett	16S rRNA	AB075768	1451 bp	Clostridium butyricum gene for 16S rRNA, partial sequence, strain: ATCC 19398
Rowett	16S rRNA	AB595129	1474 bp	Clostridium butyricum gene for 16S ribosomal RNA, partial sequence, strain: JCM 1391
Rowett	16S rRNA	AF396963	371 bp	Clostridium butyricum strain ATCC19398 16S ribosomal RNA gene, partial sequence
Rowett	16S rRNA	M59085	1516 bp	Clostridium butyricum 16S ribosomal RNA
Rowett	16S rRNA	AJ458420	1425 bp	Clostridium butyricum partial 16S rRNA gene, strain VPI3266
Rowett	16S rRNA	KU321268	1436 bp	Clostridium butyricum strain VTT E-97426 16S ribosomal RNA gene, partial sequence.
Rowett	Genome	GCA_014131795	— bp	ASM1413179v1 assembly for Clostridium butyricum DSM 10702
Rowett	Genome	GCA_006742065	— bp	ASM674206v1 assembly for Clostridium butyricum NBRC 13949
Rowett	Genome	GCA_007992895	— bp	ASM799289v1 assembly for Clostridium butyricum NBRC 13949
Rowett	Genome	GCA_000409755	— bp	Clostridium butyricum DSM 10702 Genome sequencing assembly for Clostridium butyricum DSM 10702

MCFA pathways and genes

Reverse β-oxidation (chain elongation)4 of 5 functions80%80%

Fatty acid biosynthesis (FAS II)2 of 7 functions29%29%

Show 290 annotation-derived MCFA genes

Gene	Locus	Function	Protein	Orthogroup
adhE	ATN24_00765	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	ALP88781.1	OG0001124
crt	ATN24_03150	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	ALP89192.1	OG0001394
hbd	ATN24_03170	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	ALP89196.1	OG0000229
thl	ATN24_03775	Acetyl-CoA acetyltransferase (2.3.1.9)	ALP89283.1	OG0000234
accB	ATN24_05915	Acetyl-CoA carboxylase (6.4.1.2)	ALP89685.1	OG0000212
accC	ATN24_05920	Acetyl-CoA carboxylase (6.4.1.2)	ALP89686.1	OG0000061
ldh	ATN24_06725	L-lactate dehydrogenase (1.1.1.27)	ALP89837.1	OG0000131
accC	ATN24_07075	Acetyl-CoA carboxylase (6.4.1.2)	ALP89904.1	OG0000061
accD	ATN24_07080	Acetyl-CoA carboxylase (6.4.1.2)	ALP89905.1	OG0000403
accA	ATN24_07085	Acetyl-CoA carboxylase (6.4.1.2)	ALP89906.1	OG0000885
lctP	ATN24_08890	lactate permease [Clostridium butyricum]	ALP90249.1	OG0001228
ldh	ATN24_09365	L-lactate dehydrogenase (1.1.1.27)	ALP90340.1	OG0000131
ldh	ATN24_14975	L-lactate dehydrogenase (1.1.1.27)	ALP91392.1	OG0000131
ldh	ATN24_17815	L-lactate dehydrogenase (1.1.1.27)	ALR90310.1	OG0000131
crt	ATD26_01720	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	ALS15656.1	OG0001394
hbd	ATD26_01740	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	ALS15660.1	OG0000229
thl	ATD26_02345	Acetyl-CoA acetyltransferase (2.3.1.9)	ALS15747.1	OG0000234
accB	ATD26_04475	Acetyl-CoA carboxylase (6.4.1.2)	ALS16140.1	OG0000212
accC	ATD26_04480	Acetyl-CoA carboxylase (6.4.1.2)	ALS16141.1	OG0000061
ldh	ATD26_05275	L-lactate dehydrogenase (1.1.1.27)	ALS16289.1	OG0000131
accB	ATD26_05615	Acetyl-CoA carboxylase (6.4.1.2)	ALS16355.1	OG0000212
accC	ATD26_05625	Acetyl-CoA carboxylase (6.4.1.2)	ALS16357.1	OG0000061
accD	ATD26_05630	Acetyl-CoA carboxylase (6.4.1.2)	ALS16358.1	OG0000403
accA	ATD26_05635	Acetyl-CoA carboxylase (6.4.1.2)	ALS16359.1	OG0000885
lctP	ATD26_07435	lactate permease [Clostridium butyricum]	ALS16703.1	OG0001228
ldh	ATD26_07915	L-lactate dehydrogenase (1.1.1.27)	ALS16794.1	OG0000131
ldh	ATD26_13680	L-lactate dehydrogenase (1.1.1.27)	ALS17888.1	OG0000131
adhE	ATD26_16370	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	ALS18385.1	OG0001124
ldh	ATD26_20280	L-lactate dehydrogenase (1.1.1.27)	ALS19197.1	OG0000131
crt	AZ909_01635	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	ANF12806.1	OG0001394
hbd	AZ909_01655	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	ANF12810.1	OG0000229
thl	AZ909_02225	Acetyl-CoA acetyltransferase (2.3.1.9)	ANF12896.1	OG0000234
accB	AZ909_04355	Acetyl-CoA carboxylase (6.4.1.2)	ANF13298.1	OG0000212
accC	AZ909_04360	Acetyl-CoA carboxylase (6.4.1.2)	ANF13299.1	OG0000061
ldh	AZ909_05170	L-lactate dehydrogenase (1.1.1.27)	ANF13452.1	OG0000131
accC	AZ909_05520	Acetyl-CoA carboxylase (6.4.1.2)	ANF13520.1	OG0000061
lctP	AZ909_07335	lactate permease [Clostridium butyricum]	ANF13866.1	OG0001228
ldh	AZ909_07810	L-lactate dehydrogenase (1.1.1.27)	ANF13957.1	OG0000131
ldh	AZ909_13430	L-lactate dehydrogenase (1.1.1.27)	ANF15013.1	OG0000131
adhE	AZ909_16120	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	ANF15511.1	OG0001124
ldh	AZ909_16800	L-lactate dehydrogenase (1.1.1.27)	ANF15731.1	OG0000131
crt	BBB49_01735	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	AOR92875.1	OG0001394
hbd	BBB49_01755	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	AOR92879.1	OG0000229
thl	BBB49_02365	Acetyl-CoA acetyltransferase (2.3.1.9)	AOR92966.1	OG0000234
accB	BBB49_04540	Acetyl-CoA carboxylase (6.4.1.2)	AOR93368.1	OG0000212
accC	BBB49_04545	Acetyl-CoA carboxylase (6.4.1.2)	AOR93369.1	OG0000061
ldh	BBB49_05355	L-lactate dehydrogenase (1.1.1.27)	AOR93521.1	OG0000131
accC	BBB49_05705	Acetyl-CoA carboxylase (6.4.1.2)	AOR93588.1	OG0000061
lctP	BBB49_07515	lactate permease [Clostridium butyricum]	AOR93935.1	OG0001228
ldh	BBB49_07990	L-lactate dehydrogenase (1.1.1.27)	AOR94025.1	OG0000131
ldh	BBB49_13315	L-lactate dehydrogenase (1.1.1.27)	AOR95022.1	OG0000131
adhE	BBB49_15730	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	AOR95459.1	OG0001124
ldh	BBB49_19770	L-lactate dehydrogenase (1.1.1.27)	AOR96298.1	OG0000131
ldh	NPD4_3995	L-lactate dehydrogenase (1.1.1.27)	APF21455.1	OG0000131
accD	NPD4_1419	Acetyl-CoA carboxylase (6.4.1.2)	APF21830.1	OG0000403
ldh	NPD4_1040	L-lactate dehydrogenase (1.1.1.27)	APF22643.1	OG0000131
thlA	NPD4_3376	Acetyl-CoA acetyltransferase (2.3.1.9)	APF22813.1	OG0000234
ldh	NPD4_1345	L-lactate dehydrogenase (1.1.1.27)	APF22858.1	OG0000131
accA	NPD4_1420	Acetyl-CoA carboxylase (6.4.1.2)	APF23585.1	OG0000885
crt	NPD4_36	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	APF23919.1	OG0001394
ldh	NPD4_1899	L-lactate dehydrogenase (1.1.1.27)	APF24104.1	OG0000131
lctP	NPD4_1798	transporter, lactate permease family protein [Clostridium butyricum]	APF24152.1	OG0001228
ldh	FBD76_00705	L-lactate dehydrogenase (1.1.1.27)	QCJ04964.1	OG0000131
lctP	FBD76_01205	L-lactate permease [Clostridium butyricum]	QCJ05058.1	OG0001228
accC	FBD76_03180	Acetyl-CoA carboxylase (6.4.1.2)	QCJ05439.1	OG0000061
fabZ	FBD76_03185	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	QCJ05440.1	OG0000785
accB	FBD76_03190	Acetyl-CoA carboxylase (6.4.1.2)	QCJ05441.1	OG0000212
ldh	FBD76_03535	L-lactate dehydrogenase (1.1.1.27)	QCJ05508.1	OG0000131
ldh	FBD76_04720	L-lactate dehydrogenase (1.1.1.27)	QCJ05730.1	OG0000131
adhE	FBD76_07165	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	QCJ06183.1	OG0001124
crt	FBD76_09560	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	QCJ06598.1	OG0001394
hbd	FBD76_09580	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	QCJ06602.1	OG0000229
thl	FBD76_10175	Acetyl-CoA acetyltransferase (2.3.1.9)	QCJ06688.1	OG0000234
accB	FBD76_12350	Acetyl-CoA carboxylase (6.4.1.2)	QCJ07094.1	OG0000212
accC	FBD76_12355	Acetyl-CoA carboxylase (6.4.1.2)	QCJ07095.1	OG0000061
ldh	FBD76_18690	L-lactate dehydrogenase (1.1.1.27)	QCJ08365.1	OG0000131
crt	Cbu04g_03190	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	BBK75311.1	OG0001394
hbd	Cbu04g_03230	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	BBK75315.1	OG0000229
thl	Cbu04g_04150	Acetyl-CoA acetyltransferase (2.3.1.9)	BBK75407.1	OG0000234
ldh_1	Cbu04g_20190	L-lactate dehydrogenase (1.1.1.27)	BBK77011.1	OG0000131
bcd2	Cbu04g_21120	Butyryl-CoA dehydrogenase (1.3.8.1)	BBK77104.1	OG0000034
glcA	Cbu04g_21140	L-lactate permease [Clostridium butyricum]	BBK77106.1	OG0001228
accC	Cbu04g_25440	Acetyl-CoA carboxylase (6.4.1.2)	BBK77536.1	OG0000061
ldh1	Cbu04g_26150	L-lactate dehydrogenase (1.1.1.27)	BBK77607.1	OG0000131
ldh3	Cbu04g_29510	L-lactate dehydrogenase (1.1.1.27)	BBK77943.1	OG0000131
ldh_2	Cbu04g_38050	L-lactate dehydrogenase (1.1.1.27)	BBK78797.1	OG0000131
ldh	EBL75_03665	L-lactate dehydrogenase (1.1.1.27)	QGH20728.1	OG0000131
crt	EBL75_05855	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	QGH21135.1	OG0001394
hbd	EBL75_05875	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	QGH21139.1	OG0000229
thl	EBL75_06480	Acetyl-CoA acetyltransferase (2.3.1.9)	QGH21226.1	OG0000234
accB	EBL75_08860	Acetyl-CoA carboxylase (6.4.1.2)	QGH21668.1	OG0000212
accC	EBL75_08865	Acetyl-CoA carboxylase (6.4.1.2)	QGH21669.1	OG0000061
ldh	EBL75_14125	L-lactate dehydrogenase (1.1.1.27)	QGH22658.1	OG0000131
lctP	EBL75_14600	L-lactate permease [Clostridium butyricum]	QGH22749.1	OG0001228
etfB	EBL75_14610	Electron transfer flavoprotein beta subunit	QGH22751.1	OG0004576
accC	EBL75_16410	Acetyl-CoA carboxylase (6.4.1.2)	QGH23097.1	OG0000061
accB	EBL75_16420	Acetyl-CoA carboxylase (6.4.1.2)	QGH23099.1	OG0000212
ldh	EBL75_16760	L-lactate dehydrogenase (1.1.1.27)	QGH23164.1	OG0000131
ldh	EBL75_18185	L-lactate dehydrogenase (1.1.1.27)	QGH23434.1	OG0000131
adhE	EBL75_20700	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	QGH23896.1	OG0001124
ldh	EBQ27_03665	L-lactate dehydrogenase (1.1.1.27)	QGH24769.1	OG0000131
crt	EBQ27_05855	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	QGH25174.1	OG0001394
hbd	EBQ27_05875	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	QGH25178.1	OG0000229
thl	EBQ27_06480	Acetyl-CoA acetyltransferase (2.3.1.9)	QGH25264.1	OG0000234
accB	EBQ27_08865	Acetyl-CoA carboxylase (6.4.1.2)	QGH25707.1	OG0000212
accC	EBQ27_08870	Acetyl-CoA carboxylase (6.4.1.2)	QGH25708.1	OG0000061
ldh	EBQ27_14125	L-lactate dehydrogenase (1.1.1.27)	QGH26699.1	OG0000131
lctP	EBQ27_14600	L-lactate permease [Clostridium butyricum]	QGH26791.1	OG0001228
etfB	EBQ27_14610	Electron transfer flavoprotein beta subunit	QGH26793.1	OG0004576
accC	EBQ27_16410	Acetyl-CoA carboxylase (6.4.1.2)	QGH27140.1	OG0000061
accB	EBQ27_16420	Acetyl-CoA carboxylase (6.4.1.2)	QGH27142.1	OG0000212
ldh	EBQ27_16760	L-lactate dehydrogenase (1.1.1.27)	QGH27207.1	OG0000131
ldh	EBQ27_18185	L-lactate dehydrogenase (1.1.1.27)	QGH27478.1	OG0000131
adhE	EBQ27_20705	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	QGH27941.1	OG0001124
ldh	HLV60_02165	L-lactate dehydrogenase (1.1.1.27)	QJU43208.1	OG0000131
ldh	HLV60_03370	L-lactate dehydrogenase (1.1.1.27)	QJU43436.1	OG0000131
accB	HLV60_03720	Acetyl-CoA carboxylase (6.4.1.2)	QJU43505.1	OG0000212
fabZ	HLV60_03725	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	QJU43506.1	OG0000785
accC	HLV60_03730	Acetyl-CoA carboxylase (6.4.1.2)	QJU43507.1	OG0000061
lctP	HLV60_05715	L-lactate permease [Clostridium butyricum]	QJU43886.1	OG0001228
ldh	HLV60_06215	L-lactate dehydrogenase (1.1.1.27)	QJU43979.1	OG0000131
accC	HLV60_12335	Acetyl-CoA carboxylase (6.4.1.2)	QJU45134.1	OG0000061
accB	HLV60_12340	Acetyl-CoA carboxylase (6.4.1.2)	QJU45135.1	OG0000212
thl	HLV60_14520	Acetyl-CoA acetyltransferase (2.3.1.9)	QJU45536.1	OG0000234
hbd	HLV60_15115	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	QJU45623.1	OG0000229
crt	HLV60_15135	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	QJU45627.1	OG0001394
adhE	HLV60_17525	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	QJU46043.1	OG0001124
ldh	HLV60_20125	L-lactate dehydrogenase (1.1.1.27)	QJU46608.1	OG0000131
adhE	FF104_00685	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	QMW89519.1	OG0001124
ldh	FF104_03185	L-lactate dehydrogenase (1.1.1.27)	QMW89984.1	OG0000131
ldh	FF104_04815	L-lactate dehydrogenase (1.1.1.27)	QMW90292.1	OG0000131
accB	FF104_05155	Acetyl-CoA carboxylase (6.4.1.2)	QMW90359.1	OG0000212
fabZ	FF104_05160	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	QMW90360.1	OG0000785
accC	FF104_05165	Acetyl-CoA carboxylase (6.4.1.2)	QMW90361.1	OG0000061
lctP	FF104_07250	L-lactate permease [Clostridium butyricum]	QMW90762.1	OG0001228
ldh	FF104_07715	L-lactate dehydrogenase (1.1.1.27)	QMW90850.1	OG0000131
accC	FF104_13375	Acetyl-CoA carboxylase (6.4.1.2)	QMW91928.1	OG0000061
accB	FF104_13380	Acetyl-CoA carboxylase (6.4.1.2)	QMW91929.1	OG0000212
thl	FF104_15570	Acetyl-CoA acetyltransferase (2.3.1.9)	QMW92341.1	OG0000234
hbd	FF104_16180	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	QMW92428.1	OG0000229
crt	FF104_16200	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	QMW92432.1	OG0001394
ldh	FF104_20835	L-lactate dehydrogenase (1.1.1.27)	QMW93344.1	OG0000131
ldh	KDJ93_09815	L-lactate dehydrogenase (1.1.1.27)	QUF82033.1	OG0000131
lctP	KDJ93_10325	L-lactate permease [Clostridium butyricum]	QUF82130.1	OG0001228
accC	KDJ93_12220	Acetyl-CoA carboxylase (6.4.1.2)	QUF82493.1	OG0000061
fabZ	KDJ93_12225	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	QUF82494.1	OG0000785
accB	KDJ93_12230	Acetyl-CoA carboxylase (6.4.1.2)	QUF82495.1	OG0000212
ldh	KDJ93_12575	L-lactate dehydrogenase (1.1.1.27)	QUF82561.1	OG0000131
ldh	KDJ93_13705	L-lactate dehydrogenase (1.1.1.27)	QUF82776.1	OG0000131
adhE	KDJ93_16435	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	QUF83266.1	OG0001124
crt	KDJ93_01870	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	QUF83705.1	OG0001394
hbd	KDJ93_01890	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	QUF83709.1	OG0000229
thl	KDJ93_02485	Acetyl-CoA acetyltransferase (2.3.1.9)	QUF83795.1	OG0000234
accB	KDJ93_04705	Acetyl-CoA carboxylase (6.4.1.2)	QUF84204.1	OG0000212
accC	KDJ93_04710	Acetyl-CoA carboxylase (6.4.1.2)	QUF84205.1	OG0000061
ldh	KDJ93_19230	L-lactate dehydrogenase (1.1.1.27)	QUF85196.1	OG0000131
crt	HNS01_01725	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	UTY51899.1	OG0001394
hbd	HNS01_01745	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	UTY51903.1	OG0000229
thl	HNS01_02355	Acetyl-CoA acetyltransferase (2.3.1.9)	UTY51991.1	OG0000234
ldh	HNS01_10175	L-lactate dehydrogenase (1.1.1.27)	UTY53437.1	OG0000131
lctP	HNS01_10630	L-lactate permease [Clostridium butyricum]	UTY53524.1	OG0001228
accC	HNS01_13115	Acetyl-CoA carboxylase (6.4.1.2)	UTY53989.1	OG0000061
fabZ	HNS01_13120	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	UTY53990.1	OG0000785
accB	HNS01_13125	Acetyl-CoA carboxylase (6.4.1.2)	UTY53991.1	OG0000212
ldh	HNS01_13470	L-lactate dehydrogenase (1.1.1.27)	UTY54058.1	OG0000131
ldh	HNS01_15005	L-lactate dehydrogenase (1.1.1.27)	UTY54344.1	OG0000131
adhE	HNS01_17535	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	UTY54808.1	OG0001124
ldh	HNS01_18465	L-lactate dehydrogenase (1.1.1.27)	UTY55103.1	OG0000131
ldh	O4N14_10695	L-lactate dehydrogenase (1.1.1.27)	WBP97740.1	OG0000131
lctP	O4N14_11200	L-lactate permease [Clostridium butyricum]	WBP97835.1	OG0001228
accC	O4N14_13190	Acetyl-CoA carboxylase (6.4.1.2)	WBP98217.1	OG0000061
fabZ	O4N14_13195	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	WBP98218.1	OG0000785
accB	O4N14_13200	Acetyl-CoA carboxylase (6.4.1.2)	WBP98219.1	OG0000212
ldh	O4N14_13550	L-lactate dehydrogenase (1.1.1.27)	WBP98288.1	OG0000131
ldh	O4N14_14765	L-lactate dehydrogenase (1.1.1.27)	WBP98522.1	OG0000131
adhE	O4N14_17210	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	WBP98969.1	OG0001124
crt	O4N14_01735	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	WBP99383.1	OG0001394
hbd	O4N14_01755	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	WBP99387.1	OG0000229
thl	O4N14_02345	Acetyl-CoA acetyltransferase (2.3.1.9)	WBP99474.1	OG0000234
accB	O4N14_04530	Acetyl-CoA carboxylase (6.4.1.2)	WBP99879.1	OG0000212
accC	O4N14_04535	Acetyl-CoA carboxylase (6.4.1.2)	WBP99880.1	OG0000061
ldh	O4N14_19650	L-lactate dehydrogenase (1.1.1.27)	WBQ00872.1	OG0000131
ldh	QVH08_11670	L-lactate dehydrogenase (1.1.1.27)	WJV32895.1	OG0000131
lctP	QVH08_12170	L-lactate permease [Clostridium butyricum]	WJV32990.1	OG0001228
accC	QVH08_14160	Acetyl-CoA carboxylase (6.4.1.2)	WJV33373.1	OG0000061
fabZ	QVH08_14165	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	WJV33374.1	OG0000785
accB	QVH08_14170	Acetyl-CoA carboxylase (6.4.1.2)	WJV33375.1	OG0000212
ldh	QVH08_14520	L-lactate dehydrogenase (1.1.1.27)	WJV33444.1	OG0000131
ldh	QVH08_15735	L-lactate dehydrogenase (1.1.1.27)	WJV33679.1	OG0000131
adhE	QVH08_00315	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	WJV34129.1	OG0001124
crt	QVH08_02705	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	WJV34547.1	OG0001394
hbd	QVH08_02725	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	WJV34551.1	OG0000229
thl	QVH08_03315	Acetyl-CoA acetyltransferase (2.3.1.9)	WJV34638.1	OG0000234
accC	QVH08_05505	Acetyl-CoA carboxylase (6.4.1.2)	WJV35044.1	OG0000061
ldh	QVH08_20965	L-lactate dehydrogenase (1.1.1.27)	WJV36133.1	OG0000131
ldh	Q9978_09020	L-lactate dehydrogenase (1.1.1.27)	WLS66421.1	OG0000131
ldh	Q9978_14795	L-lactate dehydrogenase (1.1.1.27)	WLS67537.1	OG0000131
adhE	Q9978_00325	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	WLS68041.1	OG0001124
crt	Q9978_02705	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	WLS68459.1	OG0001394
hbd	Q9978_02725	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	WLS68463.1	OG0000229
thl	Q9978_03335	Acetyl-CoA acetyltransferase (2.3.1.9)	WLS68553.1	OG0000234
accC	Q9978_05530	Acetyl-CoA carboxylase (6.4.1.2)	WLS68964.1	OG0000061
ldh	Q9978_06350	L-lactate dehydrogenase (1.1.1.27)	WLS69120.1	OG0000131
accB	Q9978_06695	Acetyl-CoA carboxylase (6.4.1.2)	WLS69188.1	OG0000212
fabZ	Q9978_06700	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	WLS69189.1	OG0000785
accC	Q9978_06705	Acetyl-CoA carboxylase (6.4.1.2)	WLS69190.1	OG0000061
lctP	Q9978_08530	L-lactate permease [Clostridium butyricum]	WLS69542.1	OG0001228
ldh	Q9978_18055	L-lactate dehydrogenase (1.1.1.27)	WLS70157.1	OG0000131
ldh	ACEZ2L_10730	L-lactate dehydrogenase (1.1.1.27)	XGW89697.1	OG0000131
lctP	ACEZ2L_11225	L-lactate permease [Clostridium butyricum]	XGW89790.1	OG0001228
accC	ACEZ2L_13225	Acetyl-CoA carboxylase (6.4.1.2)	XGW90171.1	OG0000061
fabZ	ACEZ2L_13230	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	XGW90172.1	OG0000785
accB	ACEZ2L_13235	Acetyl-CoA carboxylase (6.4.1.2)	XGW90173.1	OG0000212
ldh	ACEZ2L_13585	L-lactate dehydrogenase (1.1.1.27)	XGW90242.1	OG0000131
ldh	ACEZ2L_14800	L-lactate dehydrogenase (1.1.1.27)	XGW90472.1	OG0000131
adhE	ACEZ2L_17245	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	XGW90921.1	OG0001124
crt	ACEZ2L_01735	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	XGW91338.1	OG0001394
hbd	ACEZ2L_01755	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	XGW91342.1	OG0000229
thl	ACEZ2L_02350	Acetyl-CoA acetyltransferase (2.3.1.9)	XGW91430.1	OG0000234
accB	ACEZ2L_04535	Acetyl-CoA carboxylase (6.4.1.2)	XGW91835.1	OG0000212
accC	ACEZ2L_04540	Acetyl-CoA carboxylase (6.4.1.2)	XGW91836.1	OG0000061
ldh	ACEZ2L_21015	L-lactate dehydrogenase (1.1.1.27)	XGW93117.1	OG0000131
ldh	ACP1ZZ_11495	L-lactate dehydrogenase (1.1.1.27)	XSB59329.1	OG0000131
lctP	ACP1ZZ_11990	L-lactate permease [Clostridium butyricum]	XSB59421.1	OG0001228
accC	ACP1ZZ_13990	Acetyl-CoA carboxylase (6.4.1.2)	XSB59802.1	OG0000061
fabZ	ACP1ZZ_13995	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	XSB59803.1	OG0000785
accB	ACP1ZZ_14000	Acetyl-CoA carboxylase (6.4.1.2)	XSB59804.1	OG0000212
ldh	ACP1ZZ_14350	L-lactate dehydrogenase (1.1.1.27)	XSB59873.1	OG0000131
ldh	ACP1ZZ_15565	L-lactate dehydrogenase (1.1.1.27)	XSB60104.1	OG0000131
adhE	ACP1ZZ_18010	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	XSB60556.1	OG0001124
crt	ACP1ZZ_01735	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	XSB60975.1	OG0001394
hbd	ACP1ZZ_01755	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	XSB60979.1	OG0000229
thl	ACP1ZZ_02350	Acetyl-CoA acetyltransferase (2.3.1.9)	XSB61067.1	OG0000234
accB	ACP1ZZ_04535	Acetyl-CoA carboxylase (6.4.1.2)	XSB61475.1	OG0000212
accC	ACP1ZZ_04540	Acetyl-CoA carboxylase (6.4.1.2)	XSB61476.1	OG0000061
ldh	ACP1ZZ_20970	L-lactate dehydrogenase (1.1.1.27)	XSB62627.1	OG0000131
ldh	ACQR2L_10345	L-lactate dehydrogenase (1.1.1.27)	XTP11577.1	OG0000131
lctP	ACQR2L_10790	L-lactate permease [Clostridium butyricum]	XTP11665.1	OG0001228
accC	ACQR2L_12990	Acetyl-CoA carboxylase (6.4.1.2)	XTP12081.1	OG0000061
fabZ	ACQR2L_12995	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	XTP12082.1	OG0000785
accB	ACQR2L_13000	Acetyl-CoA carboxylase (6.4.1.2)	XTP12083.1	OG0000212
ldh	ACQR2L_13345	L-lactate dehydrogenase (1.1.1.27)	XTP12151.1	OG0000131
ldh	ACQR2L_14935	L-lactate dehydrogenase (1.1.1.27)	XTP12453.1	OG0000131
adhE	ACQR2L_17405	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	XTP12913.1	OG0001124
crt	ACQR2L_01895	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	XTP13355.1	OG0001394
hbd	ACQR2L_01915	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	XTP13359.1	OG0000229
thl	ACQR2L_02525	Acetyl-CoA acetyltransferase (2.3.1.9)	XTP13451.1	OG0000234
ldh	ACQR2L_20240	L-lactate dehydrogenase (1.1.1.27)	XTP14919.1	OG0000131
lctP	ACUV59_00255	L-lactate permease [Clostridium butyricum]	MGR2710986.1	OG0001228
accC	ACUV59_02085	Acetyl-CoA carboxylase (6.4.1.2)	MGR2711351.1	OG0000061
fabZ	ACUV59_02090	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	MGR2711352.1	OG0000785
accB	ACUV59_02095	Acetyl-CoA carboxylase (6.4.1.2)	MGR2711353.1	OG0000212
ldh	ACUV59_02440	L-lactate dehydrogenase (1.1.1.27)	MGR2711422.1	OG0000131
accC	ACUV59_03260	Acetyl-CoA carboxylase (6.4.1.2)	MGR2711583.1	OG0000061
accB	ACUV59_03265	Acetyl-CoA carboxylase (6.4.1.2)	MGR2711584.1	OG0000212
thl	ACUV59_05440	Acetyl-CoA acetyltransferase (2.3.1.9)	MGR2712006.1	OG0000234
hbd	ACUV59_06050	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	MGR2712098.1	OG0000229
crt	ACUV59_06070	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	MGR2712102.1	OG0001394
adhE	ACUV59_08480	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	MGR2712528.1	OG0001124
ldh	ACUV59_11210	L-lactate dehydrogenase (1.1.1.27)	MGR2713043.1	OG0000131
ldh	ACUV59_16975	L-lactate dehydrogenase (1.1.1.27)	MGR2714176.1	OG0000131
ldh	ACUV59_17485	L-lactate dehydrogenase (1.1.1.27)	MGR2714274.1	OG0000131
adhE	ACWV2B_00670	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	MHI4340161.1	OG0001124
ldh	ACWV2B_03530	L-lactate dehydrogenase (1.1.1.27)	MHI4340697.1	OG0000131
ldh	ACWV2B_05020	L-lactate dehydrogenase (1.1.1.27)	MHI4340985.1	OG0000131
accB	ACWV2B_05360	Acetyl-CoA carboxylase (6.4.1.2)	MHI4341053.1	OG0000212
fabZ	ACWV2B_05365	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	MHI4341054.1	OG0000785
accC	ACWV2B_05370	Acetyl-CoA carboxylase (6.4.1.2)	MHI4341055.1	OG0000061
lctP	ACWV2B_07225	L-lactate permease [Clostridium butyricum]	MHI4341421.1	OG0001228
ldh	ACWV2B_07725	L-lactate dehydrogenase (1.1.1.27)	MHI4341521.1	OG0000131
accC	ACWV2B_12575	Acetyl-CoA carboxylase (6.4.1.2)	MHI4342466.1	OG0000061
accB	ACWV2B_12580	Acetyl-CoA carboxylase (6.4.1.2)	MHI4342467.1	OG0000212
thl	ACWV2B_14955	Acetyl-CoA acetyltransferase (2.3.1.9)	MHI4342922.1	OG0000234
hbd	ACWV2B_15490	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	MHI4342998.1	OG0000229
crt	ACWV2B_15510	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	MHI4343002.1	OG0001394
ldh	ACWV2B_17655	L-lactate dehydrogenase (1.1.1.27)	MHI4343386.1	OG0000131
crt	AC2FRP_01880	3-hydroxybutyryl-CoA dehydratase (4.2.1.55)	MHT4848428.1	OG0001394
hbd	AC2FRP_01900	3-hydroxybutyryl-CoA dehydrogenase (1.1.1.157)	MHT4848432.1	OG0000229
thl	AC2FRP_02475	Acetyl-CoA acetyltransferase (2.3.1.9)	MHT4848516.1	OG0000234
accB	AC2FRP_04745	Acetyl-CoA carboxylase (6.4.1.2)	MHT4848954.1	OG0000212
accC	AC2FRP_04750	Acetyl-CoA carboxylase (6.4.1.2)	MHT4848955.1	OG0000061
ldh	AC2FRP_05890	L-lactate dehydrogenase (1.1.1.27)	MHT4849173.1	OG0000131
accB	AC2FRP_06265	Acetyl-CoA carboxylase (6.4.1.2)	MHT4849247.1	OG0000212
fabZ	AC2FRP_06270	3-hydroxyacyl-ACP dehydratase (4.2.1.59)	MHT4849248.1	OG0000785
accC	AC2FRP_06275	Acetyl-CoA carboxylase (6.4.1.2)	MHT4849249.1	OG0000061
lctP	AC2FRP_08735	L-lactate permease [Clostridium butyricum]	MHT4849731.1	OG0001228
ldh	AC2FRP_09200	L-lactate dehydrogenase (1.1.1.27)	MHT4849821.1	OG0000131
ldh	AC2FRP_14940	L-lactate dehydrogenase (1.1.1.27)	MHT4850921.1	OG0000131
adhE	AC2FRP_17710	Bifunctional acetaldehyde-CoA/alcohol dehydrogenase (1.2.1.10)	MHT4851440.1	OG0001124
ldh	AC2FRP_20820	L-lactate dehydrogenase (1.1.1.27)	MHT4852015.1	OG0000131

Curator-approved marker pathway assessments

These summaries use approved candidate predictions only and update after every review decision.

Assembly	Pathway rule	Approved markers	Status
No approved-marker pathway assessments.

Profile-HMM marker predictions

Approved candidates and unresolved review calls are genomic hypotheses, not evidence of expression or MCFA production.

Marker	Assembly / protein	Confidence and status	Support	Review history
No active marker predictions for this organism.

Literature and provenance

Study	DOI	Public data
No organism-linked literature indexed yet.

Profile evidence

BacDive strain record 2563: Clostridium butyricum Rowett — Curator assertion

External databases can change. mcfaKB records source links and separates experimentally reported, curator-entered and predicted information.