FUNCTIONAL ORTHOLOGY EXPLORER

Explore MCFA genes and pathway modules

Interactively inspect annotation-supported markers, orthogroups, and pathway-rule coverage across curated genomes. Genomic presence is not evidence of expression or demonstrated MCFA production.

Find genomes

Search by organism or versioned assembly accession and open its evidence record.

Filter markers

Focus on a named enzyme marker or MCFA pathway module.

Compare patterns

Expand the heatmap to compare marker copy-number patterns.

Trace evidence

Distinguish annotations, reviewed candidates, and pathway assessments.

Search organismMarkerPathway Complete selected module onlyReset

50 genomes currently visible

Marker copy-number heatmap for filtered organisms

Organism names are shown first; assembly accessions remain available as secondary identifiers. The preview is limited to the first 100 matching genomes.

Organism and assembly	Detected markers	Pathway assessments
Clostridium taeniosporum `GCA_001735765.2`Complete Genome	thlhbdcrtadhEldhlctPrnfCaccAaccCfabG	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium tagluense `GCA_026650945.1`Complete Genome	thlhbdcrtadhEaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium tagluense `GCA_030585445.1`Complete Genome	thlhbdcrtadhEaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium tetani `GCA_000007625.1`Complete Genome	thlhbdcrtbcd^×5etfBldhlctPaccD	reversebetaoxidationcore 4/4bcdetfmodule 2/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium tetani `GCA_000967115.1`Complete Genome	thlhbdbcd^×6ldhlctP	reversebetaoxidationcore 3/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium tetani `GCA_003013635.1`Complete Genome	thlhbdcrt^×3adhEldhlctPaccB^×2accCfabH	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium tetani `GCA_029636225.1`Complete Genome	thlhbdcrt^×2adhEldhlctPaccB^×2accCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium tetani `GCA_033127885.1`Complete Genome	thlhbdcrt^×3bcdldhlctPaccBaccC	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium tetani `GCA_033128025.1`Complete Genome	thlhbdcrt^×3bcdldhlctPaccC	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium tetani `GCA_033128125.1`Complete Genome	thlhbdcrt^×3bcdldhlctPaccBaccC	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium tetani `GCA_033128185.1`Complete Genome	thlhbdcrt^×3bcdldhlctPaccBaccC	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium tetani `GCA_033128205.1`Complete Genome	thlhbdcrt^×2bcdldhlctPaccC	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium tetani `GCA_033128225.1`Complete Genome	thlhbdcrt^×3bcdldhlctPaccBaccC	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium tetani `GCA_033128245.1`Complete Genome	thlhbdcrt^×3bcdldhlctPaccC	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium tetani `GCA_033128265.1`Complete Genome	thlhbdcrt^×3bcdldhlctPaccBaccC	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium tetani `GCA_033128285.1`Complete Genome	thlhbdcrt^×2bcdldhlctPaccBaccC	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium tetani `GCA_033128305.1`Complete Genome	thlhbdcrt^×3bcdldhlctP	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium tetani `GCA_037101395.1`Complete Genome	thlhbdcrt^×2adhEldhlctPrnfAaccBaccCfabHfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium tetani `GCA_045865195.1`Complete Genome	thlhbdcrt^×2adhEldhlctPrnfAaccBaccCfabHfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium thermosuccinogenes `GCA_002896855.1`Complete Genome	adhEldh^×2lctPaccBfabG	rnfcomplex 0/6reversebetaoxidationcore 0/4bcdetfmodule 0/3lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 2/8
Clostridium tyrobutyricum `GCA_001642655.1`Complete Genome	thl^×2hbdbcdetfAetfBldh^×2lctPrnfArnfBrnfCrnfDrnfErnfG	reversebetaoxidationcore 3/4bcdetfmodule 3/3rnfcomplex 6/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium tyrobutyricum `GCA_001679705.1`Complete Genome	thl^×2hbd^×2crt^×3ldh^×2lctPaccBaccC^×2fabGfabZ^×2	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 4/8
Clostridium tyrobutyricum `GCA_014170115.1`Complete Genome	hbdcrt^×3ldh^×2lctPaccBaccC^×2fabZ^×2	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 3/8
Clostridium tyrobutyricum `GCA_047783195.1`Complete Genome	thlhbdcrt^×2ldh^×2lctPrnfAaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 3/8
Coprococcus eutactus `GCA_025149915.1`Complete Genome	crt^HMMfabD^HMMfabF^HMM×2fabG^HMMrnfA^HMMrnfB^HMMrnfC^HMM	reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 3/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Coprococcus eutactus ATCC 27759 `GCA_020735705.1`Complete Genome	crt^HMMfabD^HMMfabF^HMM×2fabG^HMMrnfA^HMMrnfB^HMMrnfC^HMM	reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 3/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Coprococcus phoceensis `GCA_042854375.1`Complete Genome	accB^HMMaccD^HMMadhE^HMMfabD^HMMfabF^HMMfabG^HMMfabK^HMMfabZ^HMMrnfA^HMMrnfB^HMMrnfC^HMMrnfD^HMMrnfE^HMMrnfG^HMM	reversebetaoxidationcore 0/4bcdetfmodule 0/3rnfcomplex 6/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Eubacterium callanderi `GCA_000152245.2`Complete Genome	accB^HMMaccC^HMMaccD^HMMcrt^HMMetfA^HMMetfB^HMM×2fabD^HMMfabF^HMMfabG^HMMfabZ^HMMlctP^HMMrnfA^HMMrnfB^HMMrnfC^HMMrnfD^HMMrnfE^HMMrnfG^HMM	reversebetaoxidationcore 1/4bcdetfmodule 2/3rnfcomplex 6/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8
Eubacterium limosum `GCA_000807675.2`Complete Genome	accB^HMMaccC^HMMaccD^HMMcrt^HMMetfA^HMMetfB^HMM×2fabD^HMMfabF^HMMfabG^HMMfabZ^HMMlctP^HMMrnfA^HMMrnfB^HMMrnfC^HMMrnfD^HMMrnfE^HMMrnfG^HMM	reversebetaoxidationcore 1/4bcdetfmodule 2/3rnfcomplex 6/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8
Eubacterium maltosivorans `GCA_002441855.2`Complete Genome	accB^HMMaccC^HMMaccD^HMMcrt^HMMetfA^HMMetfB^HMM×2fabD^HMMfabF^HMMfabG^HMMfabZ^HMMlctP^HMMrnfA^HMMrnfB^HMMrnfC^HMMrnfD^HMMrnfE^HMMrnfG^HMM	reversebetaoxidationcore 1/4bcdetfmodule 2/3rnfcomplex 6/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8
Eubacterium ramulus `GCA_045002895.1`Complete Genome	accB^HMM×2accC^HMMaccD^HMMcoat^HMM×3etfA^HMMetfB^HMMfabD^HMMfabF^HMMfabG^HMMfabK^HMMfabZ^HMMhbd^HMMrnfA^HMMrnfB^HMMrnfC^HMMrnfD^HMMrnfE^HMM	reversebetaoxidationcore 1/4bcdetfmodule 2/3rnfcomplex 5/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8
Eubacterium sp. F2 `GCA_046244355.1`Complete Genome	accC^HMMadhE^HMMcrt^HMMfabF^HMMfabG^HMMfabZ^HMMhbd^HMMlctP^HMMrnfA^HMMrnfB^HMMrnfC^HMMrnfD^HMMrnfE^HMMthl^HMMaccB^HMM	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 5/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Eubacterium sp. MSJ-33 `GCA_022174665.1`Complete Genome	accA^HMMaccD^HMMcrt^HMMfabF^HMMfabG^HMMfabZ^HMM×2rnfA^HMMrnfB^HMMrnfC^HMMrnfE^HMMthl^HMM	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 4/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 4/8
Eubacterium ventriosum `GCA_025150745.1`Complete Genome	accB^HMMcrt^HMMfabD^HMMfabF^HMMfabG^HMMfabK^HMMfabZ^HMMrnfA^HMMrnfB^HMMrnfC^HMMrnfD^HMMrnfE^HMM	reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 5/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 4/8
Lacrimispora sinapis `GCA_043633585.1`Complete Genome	accB^HMMaccD^HMMadhE^HMMcoat^HMM×2crt^HMM×2etfA^HMMetfB^HMMfabD^HMMfabF^HMMfabG^HMMfabH^HMM×2fabK^HMMfabZ^HMMrnfA^HMMrnfC^HMMrnfD^HMMrnfE^HMMthl^HMM	reversebetaoxidationcore 2/4bcdetfmodule 2/3rnfcomplex 4/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 6/8
Lacrimispora sp. BS-2 `GCA_040207125.1`Complete Genome	accB^HMMaccD^HMMadhE^HMMcrt^HMMetfA^HMM×2etfB^HMM×3fabD^HMMfabF^HMMfabG^HMMfabK^HMMfabZ^HMMlctP^HMMrnfA^HMMrnfB^HMMrnfC^HMMrnfD^HMMrnfE^HMMbcd^HMM	reversebetaoxidationcore 2/4bcdetfmodule 3/3rnfcomplex 5/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Lacrimispora sp. HJ-01 `GCA_044987295.1`Complete Genome	accB^HMMaccD^HMMadhE^HMMetfA^HMMetfB^HMM×2fabD^HMMfabF^HMMfabG^HMMfabK^HMMfabZ^HMMrnfA^HMMrnfB^HMMrnfC^HMMrnfD^HMMrnfE^HMM	reversebetaoxidationcore 0/4bcdetfmodule 2/3rnfcomplex 5/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Lacrimispora xylanisolvens `GCA_017084465.1`Complete Genome	adhE^HMMcoat^HMM×4etfA^HMMetfB^HMM×3fabD^HMMhbd^HMMrnfA^HMMrnfB^HMMrnfD^HMMrnfE^HMM	reversebetaoxidationcore 1/4bcdetfmodule 2/3rnfcomplex 4/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 1/8
Lacrimispora xylanolytica `GCA_026723765.1`Complete Genome	accB^HMMaccD^HMMadhE^HMMcoat^HMM×4crt^HMM×3etfA^HMM×2etfB^HMM×2fabD^HMMfabF^HMMfabG^HMMfabH^HMM×2fabK^HMMfabZ^HMMhbd^HMMlctP^HMMrnfA^HMMrnfC^HMMrnfD^HMMrnfE^HMMthl^HMMbcd^HMM	reversebetaoxidationcore 4/4bcdetfmodule 3/3rnfcomplex 4/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 6/8
Limosilactobacillus allomucosae `GCA_039955095.1`Complete Genome	accA^HMMaccC^HMMaccD^HMMadhE^HMMfabF^HMMfabG^HMMfabI^HMMfabZ^HMM×2thl^HMMaccB^HMM×2	reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 6/8
Limosilactobacillus fermentum 3872 `GCA_000466785.3`Complete Genome	accB^HMM×2accD^HMMadhE^HMMfabF^HMMfabG^HMMfabI^HMMfabZ^HMM×2thl^HMM	reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Limosilactobacillus fermentum CECT 5716 `GCA_000210515.1`Complete Genome	accB^HMMaccD^HMMadhE^HMMfabF^HMMfabG^HMMfabI^HMMfabZ^HMM×2thl^HMM	reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Limosilactobacillus fermentum F-6 `GCA_000397165.1`Complete Genome	accB^HMM×2accA^HMMaccC^HMMaccD^HMMadhE^HMMfabF^HMMfabG^HMMfabI^HMMfabZ^HMM×2thl^HMM	reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 6/8
Limosilactobacillus fermentum IFO 3956 `GCA_000010145.1`Complete Genome	accA^HMMaccB^HMMaccC^HMMaccD^HMMadhE^HMMfabF^HMMfabG^HMMfabI^HMMfabZ^HMM×2thl^HMM	reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 6/8
Limosilactobacillus frumenti `GCA_008876665.1`Complete Genome	accA^HMMaccC^HMMaccD^HMMadhE^HMMfabF^HMMfabG^HMMfabI^HMMfabZ^HMM×2hbd^HMMthl^HMMaccB^HMM	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 6/8
Limosilactobacillus gastricus `GCA_009648555.1`Complete Genome	accA^HMMaccB^HMM×2accC^HMMaccD^HMMfabF^HMMfabG^HMMfabI^HMMfabZ^HMM×2hbd^HMMthl^HMM	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8
Limosilactobacillus ingluviei `GCA_054353015.1`Complete Genome	accA^HMMaccB^HMM×2accC^HMMaccD^HMMadhE^HMMfabF^HMMfabG^HMMfabI^HMMfabZ^HMM×2thl^HMM	reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 6/8
Limosilactobacillus mucosae `GCA_013423865.1`Complete Genome	accA^HMMaccC^HMMaccD^HMMadhE^HMMfabF^HMMfabG^HMMfabI^HMMfabZ^HMM×2thl^HMMaccB^HMM×2	reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 6/8
Limosilactobacillus mucosae LM1 `GCA_000248095.3`Complete Genome	accB^HMM×2accA^HMMaccC^HMMaccD^HMMadhE^HMMfabF^HMMfabG^HMMfabI^HMMfabZ^HMM×2thl^HMM	fattyacidbiosynthesiscore 6/8reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1
Limosilactobacillus oris `GCA_025311495.1`Complete Genome	adhE^HMMthl^HMM	reversebetaoxidationcore 1/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 0/8

Marker-linked orthogroups and proteins

Enter a marker gene to narrow the orthogroup menu. Select an orthogroup to inspect its complete imported protein records.

Marker gene Marker-linked orthogroup

Interpretation

Absence may reflect incomplete assemblies or annotations. Orthogroup membership is supporting evidence only; unannotated orthologues are not automatically promoted to confirmed enzyme calls. Pathway completeness is marker-rule completeness and is not a flux or thermodynamic prediction.