FUNCTIONAL ORTHOLOGY EXPLORER

Explore MCFA genes and pathway modules

Interactively inspect annotation-supported markers, orthogroups, and pathway-rule coverage across curated genomes. Genomic presence is not evidence of expression or demonstrated MCFA production.

Find genomes

Search by organism or versioned assembly accession and open its evidence record.

Filter markers

Focus on a named enzyme marker or MCFA pathway module.

Compare patterns

Expand the heatmap to compare marker copy-number patterns.

Trace evidence

Distinguish annotations, reviewed candidates, and pathway assessments.

Search organismMarkerPathway Complete selected module onlyReset

50 genomes currently visible

Marker copy-number heatmap for filtered organisms

Organism names are shown first; assembly accessions remain available as secondary identifiers. The preview is limited to the first 100 matching genomes.

Organism and assembly	Detected markers	Pathway assessments
Clostridium botulinum `GCA_022833145.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabGfabZ^×2	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium botulinum `GCA_024584665.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_026224615.1`Complete Genome	thlhbdcrt^×2adhEldh^×2lctP^×3accBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_026224735.1`Complete Genome	thlhbdcrt^×2adhEldh^×2lctP^×3accBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_026224755.1`Complete Genome	thlhbdcrt^×2adhEldh^×2lctP^×3accBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_027943665.1`Complete Genome	thlhbdcrtbcdldhlctPaccBaccCfabZ	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_028416655.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_028416675.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_028416695.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_029962365.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabGfabZ^×2	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium botulinum `GCA_031228685.1`Complete Genome	thlhbdcrtadhEldhlctPaccBaccCfabZ	rnfcomplex 0/6reversebetaoxidationcore 3/4bcdetfmodule 0/3lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_055273735.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabHfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium botulinum `GCA_056824335.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium budayi `GCA_055396605.1`Complete Genome	thlhbdcrtldhlctPaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_001456065.2`Complete Genome	thlhbdcrtadhEldh^×4lctPaccAaccBaccC^×2accD	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium butyricum `GCA_001465175.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccAaccB^×2accC^×2accD	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium butyricum `GCA_001646605.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccBaccC^×2	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 2/8
Clostridium butyricum `GCA_001746555.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccBaccC^×2	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 2/8
Clostridium butyricum `GCA_001886875.1`Complete Genome	thlcrtldh^×4lctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium butyricum `GCA_005145085.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_006742065.1`Complete Genome	thlhbdcrtbcdldh^×4lctPaccC	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium butyricum `GCA_009650315.1`Complete Genome	thlhbdcrtetfBadhEldh^×4lctPaccB^×2accC^×2	reversebetaoxidationcore 3/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 2/8
Clostridium butyricum `GCA_009650335.1`Complete Genome	thlhbdcrtetfBadhEldh^×4lctPaccB^×2accC^×2	reversebetaoxidationcore 3/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 2/8
Clostridium butyricum `GCA_013112415.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_014131795.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_018140655.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_024399875.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_027627495.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_030389005.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccBaccC^×2fabZ	rnfcomplex 0/6reversebetaoxidationcore 3/4bcdetfmodule 0/3lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_030758275.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccBaccC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_041937605.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_049991395.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_050366995.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_052805695.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_055694005.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium butyricum `GCA_057321305.1`Complete Genome	thlhbdcrtadhEldh^×4lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium cadaveris `GCA_020911725.1`Complete Genome	thlhbdcrt^×2adhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium carboxidivorans `GCA_001038625.1`Complete Genome	thl^×3hbd^×3crt^×3lctP^×2fabGfabZ^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium caseinilyticum `GCA_046127635.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium caseinilyticum `GCA_046127645.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium caseinilyticum `GCA_046127655.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium cellulovorans `GCA_000145275.1`Complete Genome	thl^×2crtetfAldh^×2accAaccD	reversebetaoxidationcore 2/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium chauvoei `GCA_002327185.1`Complete Genome	thlhbdcrtadhEldh^×2lctPaccC	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 1/8
Clostridium chauvoei `GCA_002327205.1`Complete Genome	thlhbdcrtadhEldh^×2lctPaccC	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 1/8
Clostridium chauvoei `GCA_004328885.1`Complete Genome	thlhbdcrtadhEldh^×2lctPrnfC^×2accBaccC	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 2/8
Clostridium chauvoei `GCA_900168365.1`Complete Genome	thlbcdldh^×2lctPaccA	reversebetaoxidationcore 2/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium cochlearium `GCA_051549575.1`Complete Genome	thlhbdcrtldhaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 3/8
Clostridium cochlearium `GCA_900187165.1`Complete Genome	thlhbdbcd^×3etfBldh^×2accD	reversebetaoxidationcore 3/4bcdetfmodule 2/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium diolis `GCA_008705175.1`Complete Genome	thl^×2hbdcrt^×4adhEldh^×4lctPrnfCaccBaccC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium drakei `GCA_003096175.1`Complete Genome	thl^×4hbd^×3crt^×5adhE^×2ldh^×2lctP^×2rnfCaccB^×2accCfabG^×2fabZ^×2	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8

Marker-linked orthogroups and proteins

Enter a marker gene to narrow the orthogroup menu. Select an orthogroup to inspect its complete imported protein records.

Marker gene Marker-linked orthogroup

Interpretation

Absence may reflect incomplete assemblies or annotations. Orthogroup membership is supporting evidence only; unannotated orthologues are not automatically promoted to confirmed enzyme calls. Pathway completeness is marker-rule completeness and is not a flux or thermodynamic prediction.