FUNCTIONAL ORTHOLOGY EXPLORER

Explore MCFA genes and pathway modules

Interactively inspect annotation-supported markers, orthogroups, and pathway-rule coverage across curated genomes. Genomic presence is not evidence of expression or demonstrated MCFA production.

Find genomes

Search by organism or versioned assembly accession and open its evidence record.

Filter markers

Focus on a named enzyme marker or MCFA pathway module.

Compare patterns

Expand the heatmap to compare marker copy-number patterns.

Trace evidence

Distinguish annotations, reviewed candidates, and pathway assessments.

Search organismMarkerPathway Complete selected module onlyReset

50 genomes currently visible

Marker copy-number heatmap for filtered organisms

Organism names are shown first; assembly accessions remain available as secondary identifiers. The preview is limited to the first 100 matching genomes.

Organism and assembly	Detected markers	Pathway assessments
Clostridium botulinum `GCA_000253195.1`Complete Genome	thlhbdbcd^×4coat^×2ldh^×2lctPrnfArnfBrnfCrnfDrnfErnfG	reversebetaoxidationcore 3/4bcdetfmodule 1/3rnfcomplex 6/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium botulinum `GCA_000307125.1`Complete Genome	thlhbdbcd^×3coat^×4ldh^×2lctP	reversebetaoxidationcore 3/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium botulinum `GCA_000789355.1`Complete Genome	thlcrt^×2ldh^×2lctP^×3accAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_000816945.1`Complete Genome	thlcrtldhlctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_000817935.1`Complete Genome	thlcrtldhlctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_000827935.1`Complete Genome	thlhbd^×2crt^×2lctPfabGfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_000827955.1`Complete Genome	thlhbd^×2crt^×2lctPfabGfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_000829015.1`Complete Genome	thlhbdbcdadhEldhlctPaccAaccBaccD	reversebetaoxidationcore 3/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_001879605.1`Complete Genome	thlcrtldhlctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_001879625.1`Complete Genome	thlcrtldhlctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_001889345.1`Complete Genome	thlcrtldhlctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_001889365.1`Complete Genome	thlcrtldhlctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_001921905.1`Complete Genome	thlcrtldhlctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_001921925.1`Complete Genome	thlcrtldhlctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_001921945.1`Complete Genome	thlcrtldhlctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_001921965.1`Complete Genome	thlcrtldhlctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_001921985.1`Complete Genome	thlcrtldhlctPaccAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_002865745.1`Complete Genome	thlhbdcrtadhEldhlctPaccAaccBaccCfabZ^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium botulinum `GCA_002865765.1`Complete Genome	thlhbdcrtadhEldhlctPaccCfabHfabZ^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_002865805.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabHfabGfabZ^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Clostridium botulinum `GCA_002865825.1`Complete Genome	thlhbdcrtadhEldhlctPaccCaccDfabGfabZ^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium botulinum `GCA_002865845.1`Complete Genome	thlhbdcrtadhEldhlctPaccCaccDfabHfabZ^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium botulinum `GCA_002865885.1`Complete Genome	thlhbdcrtadhEldhlctPaccAaccBaccCfabZ^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium botulinum `GCA_002866045.1`Complete Genome	thlhbdcrtadhEldhlctPaccCfabZ^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 2/8
Clostridium botulinum `GCA_002866125.1`Complete Genome	thlhbdcrtadhEldhlctPaccAaccBaccCfabZ^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium botulinum `GCA_002866225.1`Complete Genome	thlhbdcrtadhEldhlctPaccAaccBaccCfabZ^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium botulinum `GCA_003013615.1`Complete Genome	thlhbdcrtadhEldhrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_003013655.1`Complete Genome	thlhbdcrtadhEldhrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_003017145.1`Complete Genome	hbdcrtadhEldhrnfAaccBaccCfabZ^×2	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_003017195.1`Complete Genome	hbdcrtadhEldhrnfAaccBaccCfabZ^×2	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_003017225.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccAaccBaccCfabGfabZ^×2	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Clostridium botulinum `GCA_003017265.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccAaccBaccCfabGfabZ^×2	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Clostridium botulinum `GCA_003017335.1`Complete Genome	thlhbdcrtadhEldhfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 1/8
Clostridium botulinum `GCA_003058345.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCaccDfabHfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Clostridium botulinum `GCA_003058445.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCaccDfabHfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Clostridium botulinum `GCA_003345315.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabHfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium botulinum `GCA_003345335.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCaccDfabGfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Clostridium botulinum `GCA_007833375.1`Complete Genome	thlhbdcrtadhEldhlctPaccAaccCaccDfabHfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Clostridium botulinum `GCA_007833395.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccAaccCaccDfabHfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Clostridium botulinum `GCA_007833415.1`Complete Genome	thlhbdcrtadhEldhlctPaccAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium botulinum `GCA_007833435.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccAaccCaccDfabHfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Clostridium botulinum `GCA_007833455.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccAaccBaccCfabGfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 5/8
Clostridium botulinum `GCA_009733885.1`Complete Genome	thlhbdcrtldh^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium botulinum `GCA_014068615.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_016071375.1`Complete Genome	thlhbd^×2crt^×2ldh^×2lctPaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_016071555.1`Complete Genome	hbdcrt^×3ldhlctPaccBaccCfabZ	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_016798345.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_016838665.1`Complete Genome	thlhbdcrtadhEldhlctPrnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_017100085.1`Complete Genome	thl^×2hbd^×2crt^×3ldh^×3lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 3/8
Clostridium botulinum `GCA_017101655.1`Complete Genome	thl^×2hbd^×2crt^×3ldh^×2accB^×2accCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 3/8

Marker-linked orthogroups and proteins

Enter a marker gene to narrow the orthogroup menu. Select an orthogroup to inspect its complete imported protein records.

Marker gene Marker-linked orthogroup

Interpretation

Absence may reflect incomplete assemblies or annotations. Orthogroup membership is supporting evidence only; unannotated orthologues are not automatically promoted to confirmed enzyme calls. Pathway completeness is marker-rule completeness and is not a flux or thermodynamic prediction.