FUNCTIONAL ORTHOLOGY EXPLORER

Explore MCFA genes and pathway modules

Interactively inspect annotation-supported markers, orthogroups, and pathway-rule coverage across curated genomes. Genomic presence is not evidence of expression or demonstrated MCFA production.

Find genomes

Search by organism or versioned assembly accession and open its evidence record.

Filter markers

Focus on a named enzyme marker or MCFA pathway module.

Compare patterns

Expand the heatmap to compare marker copy-number patterns.

Trace evidence

Distinguish annotations, reviewed candidates, and pathway assessments.

Search organismMarkerPathway Complete selected module onlyReset

50 genomes currently visible

Marker copy-number heatmap for filtered organisms

Organism names are shown first; assembly accessions remain available as secondary identifiers. The preview is limited to the first 100 matching genomes.

Organism and assembly	Detected markers	Pathway assessments
Clostridium estertheticum `GCA_001877035.1`Complete Genome	thl^×2hbdcrt^×4adhE^×2ldh^×2lctPaccC^×2	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 1/8
Clostridium estertheticum `GCA_026650905.1`Complete Genome	thlhbdcrtadhEldhlctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium estertheticum `GCA_026650925.1`Complete Genome	thlhbdcrt^×2adhEldh^×2lctPaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium estertheticum `GCA_026650965.1`Complete Genome	thlhbd^×2crt^×2adhEldh^×2lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium estertheticum `GCA_026650985.1`Complete Genome	thlhbdcrt^×2ldh^×2lctPaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 3/8
Clostridium estertheticum `GCA_026651005.1`Complete Genome	thlhbd^×2crtldh^×2lctPaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 3/8
Clostridium estertheticum `GCA_026651045.1`Complete Genome	thl^×2hbdcrt^×2adhE^×2ldh^×2lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium estertheticum `GCA_027594565.1`Complete Genome	thlhbdcrt^×2adhEldh^×2lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium estertheticum `GCA_030585465.1`Complete Genome	thlhbdcrt^×2adhEldh^×2lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium estertheticum `GCA_030585485.1`Complete Genome	thlhbdcrt^×2adhEldh^×2lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium estertheticum `GCA_030585505.1`Complete Genome	thlhbdcrtadhEldh^×2lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium estertheticum `GCA_030585525.1`Complete Genome	thlhbdcrtadhEldh^×2lctPaccB^×2accC^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium estertheticum `GCA_030585545.1`Complete Genome	thlhbdcrt^×4adhEldh^×2lctPaccB^×2accC^×2fabHfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium felsineum `GCA_002006175.2`Complete Genome	thlhbd^×2crt^×2ldh^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium felsineum `GCA_002006215.2`Complete Genome	thlhbd^×2crt^×2ldh^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium felsineum `GCA_002006235.2`Complete Genome	thlhbd^×2crt^×2ldh^×3lctP	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium felsineum `GCA_002006355.2`Complete Genome	thlhbd^×2crt^×2ldh^×3	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium fermenticellae `GCA_003600355.1`Complete Genome	thl^×3hbd^×2crt^×5ldhlctPaccBaccC	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium gasigenes `GCA_017348895.1`Complete Genome	thlhbdcrtadhEldh^×2rnfAaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium gelidum `GCA_019977655.1`Complete Genome	thl^×2hbdcrtbcd^×3ldh^×3lctPaccC	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium intestinale `GCA_013781885.1`Complete Genome	thl^×2hbdcrtadhE^×2ldh^×3lctP^×2accBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium intestinale `GCA_035905475.1`Complete Genome	thl^×3hbdcrt^×2adhE^×2ldh^×3lctP^×2accBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium isatidis `GCA_002285495.1`Complete Genome	adhEldhlctPaccC	reversebetaoxidationcore 0/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 1/8
Clostridium isatidis `GCA_048319855.1`Complete Genome	adhEldhlctPaccBaccCfabZ	reversebetaoxidationcore 0/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium kluyveri `GCA_001902295.1`Complete Genome	thl^×3hbd^×2crt^×3adhEaccBaccCfabG	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium kluyveri `GCA_026240615.1`Complete Genome	thl^×3hbdcrt^×2adhEaccB^×2accCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium ljungdahlii `GCA_000143685.1`Complete Genome	thlhbd^×2etfA^×3etfB^×3lctPrnfArnfBrnfCrnfDrnfErnfGfabD	reversebetaoxidationcore 2/4bcdetfmodule 2/3rnfcomplex 6/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium ljungdahlii `GCA_045257525.1`Complete Genome	lctPrnfAaccB^×2	reversebetaoxidationcore 0/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium ljungdahlii `GCA_045257535.1`Complete Genome	rnfAaccB^×2	reversebetaoxidationcore 0/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium ljungdahlii `GCA_045257545.1`Complete Genome	adhE^×2lctPrnfAaccB^×2accC	reversebetaoxidationcore 0/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 2/8
Clostridium ljungdahlii `GCA_045257575.1`Complete Genome	adhE^×2lctPrnfAaccB^×2accCfabZ	reversebetaoxidationcore 0/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium manihotivorum `GCA_004015185.1`Complete Genome	hbdcrtadhEldh^×2accAaccBaccCaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium neonatale `GCA_919162555.1`Complete Genome	thl^×2hbdcrtbcdetfAetfBldh^×4lctP	reversebetaoxidationcore 4/4bcdetfmodule 3/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium nitrophenolicum `GCA_055391695.1`Complete Genome	thl^×3hbd^×2crt^×2adhE^×2ldhlctPrnfAaccBaccCfabHfabZ^×2	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 1/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8
Clostridium novyi `GCA_000014125.1`Complete Genome	thl^×2hbd^×2crtbcd^×2coatldhlctPaccAaccD	reversebetaoxidationcore 4/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium novyi `GCA_003614235.1`Complete Genome	thlhbd^×2crt^×3ldhlctPaccAaccBaccCaccD	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 4/8
Clostridium pasteurianum `GCA_000389635.1`Complete Genome	thl^×3crtldh^×2accAaccD	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium pasteurianum `GCA_000807175.1`Complete Genome	thl^×2hbd^×3ldh^×2lctPaccB	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium pasteurianum `GCA_000807255.1`Complete Genome	thl^×2hbd^×3ldh^×2lctPaccB	reversebetaoxidationcore 2/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium pasteurianum `GCA_001856645.1`Complete Genome	thl^×2hbd^×2crt^×3ldh^×2lctPaccAaccBaccCaccDfabGfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8
Clostridium pasteurianum `GCA_001856695.1`Complete Genome	thl^×2hbd^×2crt^×3ldh^×2lctPaccAaccBaccCaccDfabGfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 6/8
Clostridium pasteurianum `GCA_026410065.1`Complete Genome	thl^×2hbdcrt^×2adhE^×4ldh^×2lctPaccBaccCfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 3/8
Clostridium perfringens `GCA_000009685.1`Complete Genome	thlhbdcrtetfBldhlctP	reversebetaoxidationcore 3/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium perfringens `GCA_000013285.1`Complete Genome	thlhbdbcd^×2ldhlctPaccAaccD	reversebetaoxidationcore 3/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium perfringens `GCA_000013845.2`Complete Genome	thlhbdbcdldhlctPaccAaccD	reversebetaoxidationcore 3/4bcdetfmodule 1/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 2/8
Clostridium perfringens `GCA_001304735.1`Complete Genome	thlhbdbcd^×2ldhlctPrnfArnfBrnfCrnfDrnfErnfG	reversebetaoxidationcore 3/4bcdetfmodule 1/3rnfcomplex 6/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium perfringens `GCA_001579765.1`Complete Genome	thlhbdcrt^×2lctPfabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 1/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium perfringens `GCA_001579785.1`Complete Genome	thlhbdcrt^×2fabZ	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 0/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 1/8
Clostridium perfringens `GCA_001854085.1`Complete Genome	thlhbdbcd^×2ldhlctPrnfArnfBrnfCrnfDrnfErnfG	reversebetaoxidationcore 3/4bcdetfmodule 1/3rnfcomplex 6/6lactateentrysupport 2/2ethanolentrysupport 0/1fattyacidbiosynthesiscore 0/8
Clostridium perfringens `GCA_002312985.1`Complete Genome	thlhbdcrt^×2adhEldhlctPaccAaccCaccDfabG^×2	reversebetaoxidationcore 3/4bcdetfmodule 0/3rnfcomplex 0/6lactateentrysupport 2/2ethanolentrysupport 1/1fattyacidbiosynthesiscore 4/8

Marker-linked orthogroups and proteins

Enter a marker gene to narrow the orthogroup menu. Select an orthogroup to inspect its complete imported protein records.

Marker gene Marker-linked orthogroup

Interpretation

Absence may reflect incomplete assemblies or annotations. Orthogroup membership is supporting evidence only; unannotated orthologues are not automatically promoted to confirmed enzyme calls. Pathway completeness is marker-rule completeness and is not a flux or thermodynamic prediction.